79588-35-5Relevant academic research and scientific papers
Antiinflammatory agents. 3. Synthesis and pharmacological evaluation of 2-amino-3-benzoylphenylacetic acid and analogues
Walsh,Moran,Shamblee,Uwaydah,Welstead Jr.,Sancilio,Dannenburg
, p. 1379 - 1388 (2007/10/02)
A series of substituted derivatives of 2-amino-3-benzoylphenylacetic acid (amfenac) has been synthesized and evaluated for antiinflammatory, analgesic, and cyclooxygenase inhibiting activity. Several derivatives including 4'-chloro, 4'-bromo and 5-chloro, 4'-bromo were more potent than indomethacin in these assays.
