79597-59-4Relevant academic research and scientific papers
Stereoselective synthesis of the macrolactone core of (+)-neopeltolide
Raghavan, Sadagopan,Samanta, Pradip Kumar
, p. 2346 - 2349 (2012/07/01)
A stereoselective synthesis of the macrolactone core of the potent anticancer agent neopeltolide is disclosed. The key steps of the synthesis include asymmetric allylation using Krische' protocol, conjugate reduction using MacMillan's methodology, and an
Synthesis of Allyl Thioethers
Giese, Bernd,Mazumdar, Pronab
, p. 2859 - 2865 (2007/10/02)
Addition of C6H5SCl to alkenes 8, 10, and 14 yields allyl thioethers 9, 11, and 15 + 16 after thermolysis at 120 - 200 deg C.Vinyl thioethers are not observed.The influence of substituents R1 and R2 on the regioselectivity (Table 1) and the rate of the elimination (Table 2) is examined.
