79598-53-1 Usage
Uses
Used in Bioconjugation Applications:
6-Azido-hexanoic acid is used as a linker for bioconjugation, particularly for crosslinking and the synthesis of chemical probes. The terminal azide group allows conjugation with compounds containing alkyne groups through a copper(I)-catalyzed cycloaddition reaction, also known as click chemistry.
Used in Pharmaceutical Industry:
6-Azido-hexanoic acid is used as a building block in the pharmaceutical industry for the synthesis of drug candidates and the development of drug delivery systems. Its ability to form stable amide bonds with primary amine groups in the presence of activators makes it a versatile component in the design and synthesis of new pharmaceutical compounds.
Used in Chemical Synthesis:
6-Azido-hexanoic acid is used as a building block in chemical synthesis for the creation of various chemical probes and conjugates. Its reactivity with primary amine groups and alkyne compounds through click chemistry allows for the development of novel chemical entities with potential applications in research and industry.
Check Digit Verification of cas no
The CAS Registry Mumber 79598-53-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,5,9 and 8 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 79598-53:
(7*7)+(6*9)+(5*5)+(4*9)+(3*8)+(2*5)+(1*3)=201
201 % 10 = 1
So 79598-53-1 is a valid CAS Registry Number.
79598-53-1Relevant academic research and scientific papers
Solid-Phase Supports and Uses Thereof
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, (2015/09/28)
The present disclosure relates to solid-phase azide supports, methods for making solid-state azide supports, and methods for capturing alkynes using the same. The present disclosure also relates to kits for solid-phase azide supports
NEW SYNTHETIC "TRICKS". FROM ALIPHATIC AMINES AND AMIDES TO AZIDES AND/OR HOW TO CONVERT RNHCOR' INTO RNHCOR" AVOIDING DRASTIC HYDROLYSES
Garcia, Jordi,Vilarrasa, Jaume
, p. 341 - 342 (2007/10/02)
Controlled reduction of N-alkyl-N-nitrosoamides to hydrazides followed by nitrosation and fragmentation affords azides in 80percent overall yields, under mild conditions.This simple idea is the basis of methods for the conversion of alkylamines and N-alkylamides to alkyl azides, of RNHCOR' into RNHCOR" or RN(COR''')2, and of lactames into ω-azido esters or ω-azido acids.
