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Benzoic acid, 2-[[(2-hydroxy-1-naphthalenyl)methylene]amino]-, is a complex organic compound with the chemical formula C18H13NO3. It is a derivative of benzoic acid, featuring a naphthalene ring with a hydroxyl group and an imine linkage to the benzene ring. Benzoic acid, 2-[[(2-hydroxy-1-naphthalenyl)methylene]amino]- is known for its potential applications in the pharmaceutical industry, particularly as an intermediate in the synthesis of certain drugs. It exhibits a unique chemical structure that allows for specific interactions with biological targets, making it a valuable component in the development of new medications. The compound's properties, such as its solubility and reactivity, are influenced by the presence of the naphthalene and benzene rings, as well as the hydroxyl and amino groups, which can participate in various chemical reactions and interactions within a biological context.

796-47-4

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796-47-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 796-47-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,9 and 6 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 796-47:
(5*7)+(4*9)+(3*6)+(2*4)+(1*7)=104
104 % 10 = 4
So 796-47-4 is a valid CAS Registry Number.

796-47-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[(2-oxonaphthalen-1-ylidene)methylamino]benzoic acid

1.2 Other means of identification

Product number -
Other names {2-hydroxy-1-naphthylmethylene}-anthranilic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:796-47-4 SDS

796-47-4Relevant articles and documents

A turn-on type stimuli-responsive fluorescent dye with specific solvent effect: Implication for a new prototype of paper using water as the ink

Hu, Xiaochen,Liu, Yang,Duan, Yuai,Han, Jingqi,Li, Zhongfeng,Han, Tianyu

, p. 7 - 12 (2017)

In this study, we reported the photoluminescence (PL) behaviour of a new intramolecular charge transfer (ICT) compound, ((E)-2-(((2-hydroxynaphthalen-1-yl)methylene)amino)benzoic acid, (HABA), which shows ICT solvent effect in aprotic solvents as confirme

SMALL MOLECULE INHIBITORS OF A PROTEIN COMPLEX

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Paragraph 00137; 00138, (2020/12/29)

Compositions and methods for treating thrombosis, inflammation, and atherosclerosis by administration of a compound that binds to KRIT1 to inhibit binding with HEG1.

Synthesis of Chemically and Configurationally Stable Monofluoro Acylboronates: Effect of Ligand Structure on their Formation, Properties, and Reactivities

Noda, Hidetoshi,Bode, Jeffrey W.

supporting information, p. 3958 - 3966 (2015/04/14)

The recent disclosures of two classes of acylborons, potassium acyltrifluoroborates (KATs) and N-methyliminodiacetyl (MIDA) acylboronates, demonstrated that certain acylboron species can be both remarkably stable and uniquely reactive. Here we report new classes of ligands for acylboronates that have a significant influence on the formation, properties, and reactivities of acylboronates. Our systematic investigations identified a class of neutral, monofluoroboronates that can be prepared in a one step, gram-scale fashion from readily accessible KATs. These monofluoroboronates are stable to air, moisture, and silica gel chromatography and can be easily handled without any special precautions. X-ray crystallography, NMR spectroscopy, and HPLC studies showed that they are tetravalent, configurationally stable B-chiral acylboronates. Significantly, the ligands on the boronate allow for fine-tuning of the properties and reactivity of acylboronates. In amide-forming ligation with hydroxylamines under aqueous conditions, a considerable difference in reactivity was observed as a function of ligand structure. The solid-state structures suggested that subtle steric and conformational factors modulate the reactivities of the acylboronates.

Sirtuin Inhibiting Compounds

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Page/Page column 22-23, (2009/06/27)

Provided herein are compositions and methods for treating or preventing cancer and autoimmune diseases. Compositions comprise a sirtuin inhibitory compound that decreases the activity of a sirtuin, such as SIRT1 or Sir2. Exemplary methods comprise contact

Design, synthesis, and biological evaluation of sirtinol analogues as class III histone/protein deacetylase (sirtuin) inhibitors

Mai, Antonello,Massa, Silvio,Lavu, Siva,Pezzi, Riccardo,Simeoni, Silvia,Ragno, Rino,Mariotti, Francesca R.,Chiani, Francesco,Camilloni, Giorgio,Sinclair, David A.

, p. 7789 - 7795 (2007/10/03)

In a search for potent inhibitors of class III histone/protein deacetylases (sirtuins), a series of sirtinol analogues have been synthesized and the degree of inhibition was assessed in vitro using recombinant yeast Sir2, human SIRT1, and human SIRT2 and in vivo with a yeast phenotypic assay. Two analogues, namely, 3- and 4-[(2-hydroxy-1-naphthalenylmethylene)-amino]-N-(1-phenylethyl) benzamide (i.e., m- and p-sirtinol), were 2- to 10-fold more potent than sirtinol against human SIRT1 and SIRT2 enzymes. In yeast in vivo assay, these two small molecules were as potent as sirtinol. Compounds lacking the 2-hydroxy group at the naphthalene moiety or bearing several modifications at the benzene 2′-position of the aniline portion (carbethoxy, carboxy, and cyano) were 1.3-13 times less potent than sirtinol, whereas the 2′-carboxamido analogue was totally inactive. Both (R)- and (S)-sirtinol had similar inhibitory effects on the yeast and human enzymes, demonstrating no enantioselective inhibitory effect.

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