79604-91-4Relevant academic research and scientific papers
New HA 14-1 analogues: Synthesis of 2-amino-4-cyano-4H-chromenes
Moafi, Leila,Ahadi, Somayeh,Bazgir, Ayoob
scheme or table, p. 6270 - 6274 (2011/01/04)
The synthesis of 2-amino-4-cyano-4H-chromene derivatives as new HA 14-1 analogues by a simple and efficient method is reported. In addition, the reaction of 2-amino-2H-chromene-3-carbonitriles, salicylaldehydes and amines results in the formation of new c
Structure and Reactivity of 2-Amino-3-carbamoylchromenylium Salts
Rubtsov, M. I.,Lukatskaya, L. L.,Karasev, A. A.
, p. 134 - 137 (2007/10/03)
A series of 3-substituted 2-aminochromenylium salts were synthesized, and their acid dissociation constants in 50 percent ethanol were measured at 20 deg C. 2-Amino-3-carbamoylchromenylium salts showed a correlation between log Ka values and Brown-Okamoto substituent coefficient constants ?+ (ρ = 0.99, r = 0.973). The constant ?+ for the quinolizine group was estimated at -2.9. A scale of acidity (H+) was proposed for solutions of HCl in 50 vol percent ethanol at 20 deg C (cHCl ,1.5 M). The effect of substituents in positions 3, 6, and 7 and methylation of the 2-amino group on the reactivity of 2-aminochromenylium salts is discussed.
Recyclization of 2-imino-2H-1-benzopyrans under the influence of nucleophilic reagents. 2. Reaction of 2-iminocoumarin-3-carboxamides with o-aminobenzenesulfonamide
Kovalenko,Chernykh,Shkarlat,Ukrainets,Gridasov,Rudnev
, p. 791 - 795 (2007/10/03)
2-Iminocoumarin-3-carboxamides recyclized into 3-(1,1-dioxo-2H-benzo-1,2,4-thiadiazinyl-3)coumarins under the influence of o-aminobenzenesulfonamide. An alternative method of synthesis is discussed. Proposed mechanisms for the recyclization are discussed.
Recyclization of 2-imino-2H-1-benzopyrans using nucleophilic reagents 3. Reaction of 2-iminocoumarin-3-carboxamides with o-phenylenediamines and o-amino(thio)phenols
Kovalenko,Vasil'ev,Sorokina,Chernykh,Turov,Rudnev
, p. 1412 - 1415 (2007/10/03)
Using o-phenylenediamines, o-aminophenol or o-aminothiophenol, 2-iminocoumarin-3-carboxamide can be recyclized to the corresponding 3-(1H-benzimidazol-2-yl), 3-(benzoxazol-2-yl), or 3-(benzothiazol-2-yl) coumarins. An alternative synthesis has been carried out and an analytical comparison of the synthetic routes made.
