76693-35-1

Basic information

• Product Name: 6-BROMO-3-CYANOCOUMARIN
• Synonyms: 6-BROMO-3-CYANOCOUMARIN
• CAS NO: 76693-35-1
• Molecular Formula: C10H4BrNO2
• Molecular Weight: 250.05
• Mol File: 76693-35-1.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 403.4 °C at 760 mmHg
• Flash Point: 197.8 °C
• Appearance: /
• Density: 1.78 g/cm³
• CAS DataBase Reference: 6-BROMO-3-CYANOCOUMARIN(CAS DataBase Reference)
• NIST Chemistry Reference: 6-BROMO-3-CYANOCOUMARIN(76693-35-1)
• EPA Substance Registry System: 6-BROMO-3-CYANOCOUMARIN(76693-35-1)

Safety Data

• Hazardous Substances Data: 76693-35-1(Hazardous Substances Data)

Usage

General Description

6-Bromo-3-cyanocoumarin is a chemical compound that belongs to the coumarin family and contains a bromine atom and a nitrile group. It is commonly used as a fluorescent probe in biological and chemical research, as it emits a blue light when exposed to UV radiation. This property makes it particularly useful in labeling and tracking various biological molecules and processes. Additionally, 6-Bromo-3-cyanocoumarin has been studied for its potential applications in medicine, including as a fluorescent tag for imaging and diagnosing cancerous tissues. Overall, its unique fluorescent properties and potential biomedical uses make 6-Bromo-3-cyanocoumarin an important and versatile chemical compound in various fields of research and technology.

Upstream product

• 109-77-3 malononitrile 
• 1761-61-1 5-bromosalicyclaldehyde 
• 105-56-6 ethyl 2-cyanoacetate 
• 372-09-8 cyanoacetic acid 
• 140-87-4 Cyanoacetohydrazide 
• 2199-90-8 ethyl 6-bromo-2-oxo-2H-chromene-3-carboxylate 
• 79604-91-4 6-Bromo-2-imino-2H-chromene-3-carboxylic acid amide 

Downstream Products

• 2199-87-3 6-bromocoumarin-3-carboxylic acid 

Relevant articles and documents

One-Pot Green Synthesis of 2-Oxo-2H-chromene-3-carbonitriles Using Dual-Frequency Ultrasonication

Abstract: A green synthesis of 2-oxo-2H-chromene-3-carbonitriles has been carried out in one step by reacting 2-hydroxybenzaldehydes or 2-hydroxyacetophenones with ethyl cyanoacetate under dual-frequency ultrasonica-tion (ultrasonic bath of 40 KHz and probe of 20 KHz). The compounds were obtained in very high yield, and their structures were confirmed by IR and NMR data.

Zirconium(IV) oxychloride: A simple and efficient catalyst for the synthesis of chromen-2-one derivatives

The present work explores a highly efficient, environmental friendly, green protocol for the synthesis of chromen-2-one derivatives (3a-m) by the condensation of salicylaldehydes with various active methylene compounds using zirconium (IV) oxychloride as catalyst. This is a convenient and rapid method for Knoevenagel condensation and this methodology offers several advantages including shorter reaction time, milder conditions, inexpensive catalyst, simple operational procedure and allowed to achieve the desired products in excellent yields. The structures of all the synthesized compounds were confirmed by spectral data.

ZIF-8 nanoparticles as an efficient and reusable catalyst for the Knoevenagel synthesis of cyanoacrylates and 3-cyanocoumarins

Zeolitic imidazolate framework (ZIF-8) particles with an average size of ca. 355 nm and a specific surface area of 1786 m2.g?1were used as an heterogenous catalyst for the Knoevenagel synthesis of α,β-unsaturated cyanoesters and 3-cy