79636-77-4

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 79-77-6 (E)-β-ionone 

Downstream Products

• 79194-89-1 N-Methyl-N-[(E)-3-oxo-5-(2,6,6-trimethyl-cyclohex-1-enyl)-pent-4-enyl]-acetamide 
• 125281-65-4 3,3-Dimethyl-6-<2-(2,6,6-trimethyl-1-cyclohexen-1-yl)ethenyl>-2H-pyran-2,4(3H)-dion 
• 362049-75-0 (E)-5-Phenylsulfanyl-1-(2,6,6-trimethyl-cyclohex-1-enyl)-pent-1-en-3-one 
• 362049-77-2 [(E)-3-Methylene-5-(2,6,6-trimethyl-cyclohex-1-enyl)-pent-4-ene-1-sulfonyl]-benzene 
• 362049-76-1 [(E)-3-Methylene-5-(2,6,6-trimethyl-cyclohex-1-enyl)-pent-4-enylsulfanyl]-benzene 
• 14393-45-4 (E)-3-(2,6,6-trimethylcyclohex-1-enyl)acrylic acid 
• 125281-77-8 7-<2-(2,6,6-Trimethyl-1-cyclohexen-1-yl)ethenyl>-6-oxaspiro<3.5>non-7-en-5,9-dion 
• 432-25-7 2,6,6-trimethylcyclohex-1-enecarbaldehyde 

Relevant academic research and scientific papers

Synthesis of new ethyl 9-methylene-13E and 13Z-retinoates via the Julia olefination reaction

Synthesis of new ethyl 9-methylene-13E and 13Z-retinoates via the 9-methylene C-15 sulphone 5 is reported. The Julia olefination strategy was used for building the C-20 skeleton.

Representative Metalation and Reduction Reactions of the Superactive Metal Hydrides LiH, NaH, and KH

Unusually active alkali metal hydrides, LiH, NaH, and KH, can be prepared easily from hydrogen and superbasic reagents.The synthetic utility of these active hydrides has been explored.Thus, carbonyl and thiocarbonyl compounds, alcohols, dimethyl sulfoxide

The Cyclopropane Ring as a Reporter of Radical Leaving-Group Reactivity for Ni-Catalyzed C(sp3)-O Arylation

The ability to understand and predict reactivity is essential for the development of new reactions. In the context of Ni-catalyzed C(sp3)-O functionalization, we have developed a unique strategy employing activated cyclopropanols to aid the design and optimization of a redox-active leaving group for C(sp3)-O arylation. In this chemistry, the cyclopropane ring acts as a reporter of leaving-group reactivity, since the ring-opened product is obtained under polar (2e) conditions, and the ring-closed product is obtained under radical (1e) conditions. Mechanistic studies demonstrate that the optimal leaving group is redox-active and are consistent with a Ni(I)/Ni(III) catalytic cycle. The optimized reaction conditions are also used to synthesize a number of arylcyclopropanes, which are valuable pharmaceutical motifs.

INFECTION DETECTION METHODS AND SYSTEMS AND RELATED COMPOUNDS AND COMPOSITIONS

A compound, or a pharmaceutically acceptable salt, ester, hydrate or solvate thereof, comprising formula I: A-B wherein A comprises a carbohydrate that is a neuraminidase or galactosidase substrate; B comprises an odorant moiety; B is covalently bonded to