796848-83-4Relevant academic research and scientific papers
Mild and reliable cleavage sequence for phenoxy acetates
Mirk, Daniela,Waldvogel, Siegfried R.
, p. 7911 - 7914 (2004)
A novel combination of reliable transformations like ester saponification and subsequent Curtius-rearrangement employing mild reaction conditions, offers the first synthetically interesting strategy for the removal of methoxycarbonylmethyl groups from phenolic oxygens. This methodology gives also access to labile iodosubstituted phenols. A novel combination of reliable transformations like ester saponification and subsequent Curtius-rearrangement employing mild reaction conditions, offers the first synthetically interesting strategy for the removal of methoxycarbonylmethyl groups from phenolic oxygens. This methodology gives also access to labile iodosubstituted phenols.
