796851-03-1

Basic information

• Product Name: Pyridine, 2,5-dichloro-4-iodo-
• Synonyms: Pyridine, 2,5-dichloro-4-iodo-;2,5-Dichloro-4-iodopyridine
• CAS NO: 796851-03-1
• Molecular Formula: C₅H₂Cl₂IN
• Molecular Weight: 273.89
• Product Categories: Propidium heterocyclic series
• Mol File: 796851-03-1.mol
• Article Data: 7

Chemical Properties

• Melting Point: 140 ºC
• Boiling Point: 279 ºC
• Flash Point: 122 ºC
• Appearance: /
• Density: 2.129
• Refractive Index: 1.652
• Storage Temp.: Refrigerated.
• CAS DataBase Reference: Pyridine, 2,5-dichloro-4-iodo-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 2,5-dichloro-4-iodo-(796851-03-1)
• EPA Substance Registry System: Pyridine, 2,5-dichloro-4-iodo-(796851-03-1)

Safety Data

• Hazardous Substances Data: 796851-03-1(Hazardous Substances Data)

Usage

Description

Pyridine, 2,5-dichloro-4-iodo-, is an organic chemical compound characterized by its molecular formula C5H2Cl2IN. It features a six-membered heterocyclic pyridine ring with chlorine and iodine substituents at the 2nd and 5th positions, respectively. Pyridine, 2,5-dichloro-4-iodois a versatile intermediate in the synthesis of various chemical products, including pharmaceuticals, agricultural chemicals, and other fine chemicals. Its unique reactivity and versatility make it a valuable building block in organic synthesis, primarily utilized in research and development laboratories.

Uses

Used in Pharmaceutical Industry:
Pyridine, 2,5-dichloro-4-iodo-, is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and reactivity allow for the development of new drugs with specific therapeutic properties.
Used in Agricultural Chemical Industry:
Pyridine, 2,5-dichloro-4-iodois also employed as an intermediate in the production of agricultural chemicals, contributing to the development of effective pesticides and other agrochemicals.
Used in Organic Synthesis:
Pyridine, 2,5-dichloro-4-iodo-, is used as a building block in organic synthesis, enabling the creation of a wide range of chemical compounds with diverse applications.
Used in Research and Development Laboratories:
Due to its unique reactivity and versatility, this compound is extensively used in research and development laboratories for exploring new chemical reactions and developing innovative synthetic routes.

InChI:InChI=1/C5H2Cl2IN/c6-3-2-9-5(7)1-4(3)8/h1-2H

Upstream product

• 16110-09-1 2,5 dichloropyridine 

Downstream Products

• 1201935-46-7 2-[(2,5-dichloropyridin-4-yl)amino]-N-methoxy-N-methylbenzamide 
• 1201935-60-5 2-[(2,5-dichloropyridin-4-yl)amino]-6-fluoro-N-methylbenzamide 
• 1061358-83-5 2-[(2,5-dichloropyridin-4-yl)amino]-N-methylbenzamide 
• 1201935-59-2 2-[(2,5-dichloropyridin-4-yl)amino]-3-fluoro-N-methylbenzamide 
• 1201935-41-2 2-[(2,5-dichloro-4-pyridinyl)amino]-N-(methyloxy)benzamide 
• 1201933-80-3 2-((5-chloro-2-((1-(2-oxo-2-(pyrrolidin-1-yl)-ethyl)pyrazol-4-yl)amino)-4-pyridyl)amino)-N-methyl-benzamide 
• 1201933-98-3 2-((5-chloro-2-((1-(4-piperidyl)pyrazol-4-yl)amino)-4-pyridyl)amino)-N-methyl-benzamide 
• 1201933-99-4 2-((5-chloro-2-((1-(1-methyl-4-piperidyl)pyrazol-4-yl)amino)-4-pyridyl)amino)-N-methoxy-N-methyl-benzamide 
• 1201935-43-4 2-[4-[[5-chloro-4-[[2-(methylcarbamoyl)phenyl]amino]pyridin-2-yl]amino]pyrazol-1-yl]acetic acid 
• 1201934-21-5 2-((5-chloro-2-((1,3-dimethylpyrazol-4-yl)amino)-4-pyridyl)amino)-6-fluoro-N-methyl-benzamide 
• 1201933-85-8 2-((5-chloro-2-((5-methoxy-2-methylpyrazol-3-yl)amino)pyridin-4-yl)amino)-N-methylbenzamide 
• 1201933-78-9 2-({5-Chloro-2-[(1,3-dimethyl-1H-pyrazol-4-yl)-amino]-4-pyridinyl}amino)-N-(methyloxy)benzamide 
• 1201934-20-4 2-((5-chloro-2-((1,3-dimethylpyrazol-4-yl)amino)-4-pyridyl)amino)-3-fluoro-N-methyl-benzamide 

Relevant articles and documents

POLYSUBSTITUTED PYRIDINE COMPOUND, PREPARATION METHOD, USE AND PHARMACEUTICAL COMPOSITION

The present invention provides a polysubstituted pyridine compound of Formula I, a preparation method, a use and a pharmaceutical composition thereof. The polysubstituted pyridine compound of Formula I according to the present invention has an excellent anti-tumor effect, can inhibit various cell kinases simultaneously, has significantly excellent pharmacokinetic characteristics, and is very suitable for oral and intravenous administration. The pharmaceutical composition according to the present invention can be useful for treating tumors and cancers.

Deprotonative metalation of chloro- and bromopyridines using amido-based bimetallic species and regioselectivity-computed CH acidity relationships

A series of chloro- and bromopyridines have been deprotometalated by using a range of 2,2,6,6-tetramethylpiperidino-based mixed lithium-metal combinations. Whereas lithium-zinc and lithium-cadmium bases afforded different mono- and diiodides after subsequent interception with iodine, complete regioselectivities were observed with the corresponding lithium-copper combination, as demonstrated by subsequent trapping with benzoyl chlorides. The obtained selectivities have been discussed in light of the CH acidities of the substrates, determined both in the gas phase and as a solution in THF by using the DFT B3LYP method.

PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST

A pyridine compound represented by the following general formula (1); the pyridine compound in which R1 is a C1-C3 fluoroalkyl group or a C1-C3 fluoroalkoxy group; the pyridine compound in which R2 is a hydrogen atom; the pyridine compound in which R2 is a group represented by Q1; a pesticidal composition containing the pyridine compound as an active ingredient; and a method of controlling a pest including applying an effective amount of the pyridine compound to the pest or a place where the pest inhabits, are provided.