796875-13-3Relevant articles and documents
DIARYLTRIAZOLMETHYLAMINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF
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Page/Page column 5, (2009/01/20)
The invention concerns compounds of formula (I): Wherein X, R1, R2, R3 and R4 are as described herein. The invention also concerns a method for preparing same and the therapeutic use thereof.
Potent imidazole and triazole CB1 receptor antagonists related to SR141716
Dyck, Brian,Goodfellow, Val S.,Phillips, Teresa,Grey, Jonathan,Haddach, Mustapha,Rowbottom, Martin,Naeve, Gregory S.,Brown, Brock,Saunders, John
, p. 1151 - 1154 (2007/10/03)
Diarylimidazolecarboxamides and diaryltriazolecarboxamides related to SR141716 were synthesized and tested for binding to the human CB1 receptor. Suitably substituted imidazoles are comparably potent to the clinical candidate, whereas the analo