796882-45-6

Usage

Uses

Used in Pharmaceutical Development:
1-((tert-Butoxycarbonyl)aMino)-2,2-difluorocyclopropanecarboxylic acid is used as a key intermediate in the synthesis of pharmaceuticals for its potential applications in developing new drugs. The presence of the tert-butoxycarbonyl group allows for mild deprotection conditions, facilitating the preparation of various biologically active molecules.
Used in Agrochemical Synthesis:
In the agrochemical industry, 1-((tert-Butoxycarbonyl)aMino)-2,2-difluorocyclopropanecarboxylic acid is utilized as a versatile building block for the creation of agrochemicals. Its unique structure contributes to the development of effective compounds for crop protection and pest control.
Used in Organic Synthesis:
1-((tert-Butoxycarbonyl)aMino)-2,2-difluorocyclopropanecarboxylic acid serves as a valuable intermediate in organic synthesis. Its cyclopropanecarboxylic acid framework, along with the protected amino group and fluorine atoms, makes it a suitable candidate for the construction of complex organic molecules and the exploration of novel chemical reactions.

InChI:InChI=1/C9H13F2NO4/c1-7(2,3)16-6(15)12-8(5(13)14)4-9(8,10)11/h4H2,1-3H3,(H,12,15)(H,13,14)

Upstream product

• 228580-19-6 (R)-(+)-{2,2-difluoro-1-[(tert-butoxy)carbonylamino]cyclopropyl}methyl acetate 
• 597556-00-8 (S)-(-)-{2,2-difluoro-1-[(tert-butoxy)carbonylamino]cyclopropyl}methyl acetate 

Relevant academic research and scientific papers

Studies of 1-Amino-2,2-difluorocyclopropane-1-carboxylic Acid: Mechanism of Decomposition and Inhibition of 1-Aminocyclopropane-1-carboxylic Acid Deaminase

1-Amino-2,2-difluorocyclopropane-1-carboxylic acid (DFACC) is of interest in the study of 1-aminocyclopropane-1-carboxylic acid (ACC) deaminase due to the increased reactivity of its cyclopropyl functionality. It is shown that DFACC is unstable under near

COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS

The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.

Efficient synthesis of (R)- and (S)-1-amino-2,2-difluorocyclopropanecarboxylic acid via lipase-catalyzed desymmetrization of prochiral precursors

The asymmetric syntheses of (+)-(R)-1-amino-2,2-difluorocyclopropane-1-carboxylic acid and its enantiomer have been accomplished. Key reactions in the synthetic design are lipase-catalyzed desymmetrization of a prochiral diol and a prochiral diacetate.

Synthesis of (+)-(R)-1-Amino-2,2-difluorocyclopropane-1-carboxylic acid through lipase-catalyzed asymmetric acetylation

(+)-(R)-1-Amino-2,2-difluorocyclopropane-1-carboxylic acid was synthesized via the lipase-catalyzed asymmetric acetylation of a pro-chiral diol as the key step.