796965-82-7Relevant academic research and scientific papers
Synthesis and resolution of a key building block for epothilones: A comparison of asymmetric synthesis, chemical and enzymatic resolution
Scheid, Guenther,Ruijter, Eelco,Konarzycka-Bessler, Monika,Bornscheuer, Uwe T.,Wessjohann, Ludger A.
, p. 2861 - 2869 (2004)
The asymmetric synthesis and kinetic resolution of a series of acyloins (α-hydroxy ketones) suitable as building blocks for the northern half of epothilones was studied. Three methods were applied to obtain nonracemic compounds at the eventual epothilone
