79698-13-8

Usage

InChI:InChI=1/C7H13FO5/c1-12-7-4(8)6(11)5(10)3(2-9)13-7/h3-7,9-11H,2H2,1H3/t3-,4-,5+,6-,7-/m1/s1

Upstream product

• 93960-41-9 (3aS,4R,6R,7S,7aR)-6-Methoxy-2,2-dimethyl-4-trityloxymethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-7-ol 
• 93960-43-1 methyl-3,4-O-isopropylidene-2-O-(trifluoromethanesulfonyl)-6-O-trityl-β-D-talopyranoside 
• 66295-15-6 (3aS,4R,6R,7aS)-6-Methoxy-2,2-dimethyl-4-trityloxymethyl-dihydro-[1,3]dioxolo[4,5-c]pyran-7-one 
• 34698-24-3 methyl 3,4-O-isopropylidene-6-O-trityl-β-D-galactopyranoside 
• 93960-45-3 methyl 2-deoxy-2-fluoro-3,4-O-isopropylidene-6-O-trityl-β-D-galactopyranoside 
• 67-56-1 methanol 
• 75414-46-9 2-deoxy-2-fluoro-α-D-galactopyranosyl fluoride 

Relevant academic research and scientific papers

NEW SYNTHESIS OF 2-DEOXY-2-FLUORO-D-GALACTOSE

A nucleophilic displacement reaction of methyl 3,4-O-isopropylidene-2-O-(trifluoromethanesulfonyl)-6-O-trityl-β-D-talopyranoside (10) with tetraalkylammonium fluorides in acetonitrile gave methyl 2-deoxy-2-fluoro-3,4-O-isopropylidene-6-O-trityl-β-D-galact

Preparation of two methyl deoxyfluoro-beta-D-galactopyranosides, and their interaction with galactan-specific immunoglobulin A J539 (Fab').

Methyl 2-deoxy-2-fluoro-beta-D-glactopyranoside (2) and methyl 4-deoxy-4-fluoro-beta-D-glactopyranoside (7) have been prepared, and the possibility of their binding to (1 leads to 6)-beta-D-galactopyranan-specific immunoglobulin A J539 (Fab') has been investigated. Compound 2 does not show binding, whereas 7 does. It appears that the 2-hydroxyl group of methyl beta-D-galactopyranoside may take part in hydrogen bonding to the protein.