79735-03-8

Upstream product

• 67-56-1 methanol 
• 1393359-56-2 tert-butyl (1R,2S,3S,5S)-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate 
• 1393359-52-8 tert-butyl (1S,2S,7R)-2-hydroxy-7-{[(1R)-1-(4-methoxyphenyl)ethyl](methyl)amino}cyclohept-3-ene-1-carboxylate 
• 1393359-57-3 tert-butyl (1R,2S,3R,4R,5S)-3-hydroxy-4-iodo-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate 
• 1393359-48-2 tert-butyl (2S,3R)-2-[(1S)-1-hydroxyprop-2-en-1-yl]-3-{[(1R)-1-(4-methoxyphenyl)ethyl](methyl)amino}hept-6-enoate 
• 270901-71-8 tert-butyl (E)-hepta-2,6-dienoate 

Downstream Products

• 131829-34-0 (+)-Allopseudococaine hydrochloride 
• 478-73-9 (+)-pseudococaine 
• 53-21-4 Pseudococaine hydrochloride 
• 47195-07-3 (+)-cocaine 

Relevant academic research and scientific papers

Asymmetric synthesis of the tropane alkaloid (+)-pseudococaine via ring-closing iodoamination

Ring-closing iodoamination of tert-butyl 2-hydroxy-7-[N-methyl-N-(α- methyl-p-methoxybenzyl)amino]cyclohept-3-ene-1-carboxylates proceeds with concomitant loss of the N-α-methyl-p-methoxybenzyl group to give the corresponding 8-azabicyclo[3.2.1]octane sca