79759-40-3Relevant academic research and scientific papers
Potassium hydroxide/dimethyl sulfoxide promoted intramolecular cyclization for the synthesis of benzimidazol-2-ones
Beyer, Astrid,Reucher, Christine M. M.,Bolm, Carsten
supporting information; experimental part, p. 2876 - 2879 (2011/07/07)
A new protocol for intramolecular N-arylations of ureas to form benzimidazol-2-ones has been developed. The cyclization reaction occurs in the presence of KOH and DMSO at close to ambient temperature. Under these conditions the yields are high and a wide
