797805-10-8Relevant articles and documents
Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 3. Effect of replacing the inner polymethylene chain with cyclic moieties
Tumiatti, Vincenzo,Andrisano, Vincenza,Banzi, Rita,Bartolini, Manuela,Minarini, Anna,Rosini, Michela,Melchiorre, Carlo
, p. 6490 - 6498 (2004)
In the present paper we expanded SAR studies of 3, the ethyl analogue of the AChE inhibitor caproctamine (2), by investigating the role of its octamethylene spacer separating the two amide functions through the replacement with dipiperidine and dianiline