79781-00-3 Usage
Uses
Used in Pharmaceutical Industry:
Compound 80-53 is used as an anti-malarial drug for its efficient anti-relapse activity against the Plasmodium vivax parasite, which accumulates in the liver and causes relapses. It is safer than its preceding candidate, primaquine, and is used in combination with chloroquine for effective treatment against malaria.
Used in Drug Development:
Compound 80-53 is used as a promising candidate for drug development in the pharmaceutical industry due to its improved safety profile and efficient anti-relapse activity. Its stability at pH 7-8 and hydrolysis to primaquine under acidic conditions make it a suitable candidate for further research and development in the fight against malaria.
Brand Name: Aablaquin
Originator
CDRI (India)
Check Digit Verification of cas no
The CAS Registry Mumber 79781-00-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,7,8 and 1 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 79781-00:
(7*7)+(6*9)+(5*7)+(4*8)+(3*1)+(2*0)+(1*0)=173
173 % 10 = 3
So 79781-00-3 is a valid CAS Registry Number.
InChI:InChI=1/C21H27N3O3/c1-14(6-4-9-22-15(2)18-8-11-27-21(18)25)24-19-13-17(26-3)12-16-7-5-10-23-20(16)19/h5,7,10,12-14,22,24H,4,6,8-9,11H2,1-3H3/b18-15+
79781-00-3Relevant academic research and scientific papers
Reaction of α-Acetylbutyrolactone with Amines and Hydrazine
Bhat, Balkrishen,Seth, M.,Bhaduri, A. P.
, p. 703 - 705 (2007/10/02)
The ring-opening of α-acetylbutyrolactone with primary amines and hydrazine may follow either a 5-exo-tet or 5-exo-trig ring closure reaction.This aspect has been studied by identifying the reaction product of α-acetylbutyrolactone with primary amines.The structural assignments of these products have been made on the basis of chemical degradation and spectroscopic data.
