79782-30-2

Upstream product

• 99-91-2 para-chloroacetophenone 
• 98-95-3 nitrobenzene 
• 932-98-9 1-chloro-4-nitroso-benzene 
• 98-86-2 acetophenone 
• 1316302-72-3 C₁₇H₁₂Cl₂O₂S 
• 62-53-3 aniline 
• 823-86-9 N-(4-chlorophenyl)hydroxylamine 
• 104430-34-4 N-(p-chlorophenyl)-benzoylnitrone 

Downstream Products

• 79782-33-5 1,4-bis-(4-chloro-phenyl)-butane-1,2,4-trione 

Relevant academic research and scientific papers

Substrate-controlled and highly stereoselective synthesis of 2-aminobut-2-ene-1, 4-diones

2-Methylthio-substituted 1,4-enediones, obtained from readily available aryl methyl ketones, were reacted with primary or secondary amines to afford the desired 1,4-diaryl-2-aminobut-2-ene-1,4-diones in excellent yields with high Z/E-stereoselectivity.

Synthesis, Structure, and Reactivity of 1,4-Diaryl-2-(arylamino)but-2-ene-1,4-diones

The one-pot synthesis of the title compounds (1) is achieved by reacting acetophenones and nitrobenzenes in 2-propanol with potassium 2-propoxide.The stereochemistry of the 2-butenes has been determined to be Z from an X-ray analysis.Hydrolysis and reaction with hydrazine are reported as examples of the reactivity of the title compounds.