79791-29-0

Basic information

• Product Name: Pentanoyl chloride, 5-(2,5-dimethylphenoxy)-2,2-dimethyl-
• CAS NO: 79791-29-0
• Molecular Formula: C15H21ClO2
• Molecular Weight: 268.784
• Mol File: 79791-29-0.mol
• Article Data: 22

Chemical Properties

• CAS DataBase Reference: Pentanoyl chloride, 5-(2,5-dimethylphenoxy)-2,2-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Pentanoyl chloride, 5-(2,5-dimethylphenoxy)-2,2-dimethyl-(79791-29-0)
• EPA Substance Registry System: Pentanoyl chloride, 5-(2,5-dimethylphenoxy)-2,2-dimethyl-(79791-29-0)

Safety Data

• Hazardous Substances Data: 79791-29-0(Hazardous Substances Data)

Upstream product

• 25812-30-0 gemfibrozil 

Downstream Products

• 1032597-21-9 C₁₆H₂₅NO₃ 
• 1174762-98-1 5-(2,5-dimethylphenoxy)-2,2-dimethyl-N-(perfluorophenyl)pentanamide 
• 1257521-31-5 5-(2,5-dimethylphenoxy)-2,2-dimethyl-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)pentanamide 
• 1416548-86-1 C₂₈H₃₇NO₃S 

Relevant articles and documents

Nickel-catalyzed direct thioetherification of β-C(sp3)-H bonds of aliphatic amides

The nickel-catalyzed β-thioetherification of unactivated C(sp3)-H bond of propionamides is established with the assistance of 8-aminoquinoline auxiliary, leading to the β-thio carboxylic acid derivatives. A broad range of functional groups is compatible with this thioetherfication reaction. The process represents the first successful example of metal-catalyzed C-S bond formation from unactivated C(sp3)-H bonds.

Photoredox-Catalyzed Difunctionalization of Unactivated Olefins for Synthesizing Lactam-Substituted gem-Difluoroalkenes

Herein, the synthesis of lactam-substituted gem-difluoroalkenes has been developed through a photoredox-catalyzed radical cascade reaction. This developed photoredox-catalyzed, Br?nsted base-assisted intramolecular 5-exo-trig cyclization/intermolecular radical addition/β-fluoride elimination reaction offers a simple method for producing lactam, carbamate, or urea-substituted gem-difluoroalkenes with good functional group tolerance and high yields.

Synthesis, characterization and evaluation of gemfibrozil-stilbene hybrid as antioxidant agent

Background: Oxidative stress and inflammation are important processes involved in cardiovascular disease. Antioxidant agents, like drugs or natural products from plants or plant-based food, represent a promising approach to treat these pathologies. Methods: In light of this, a gemfibrozil-stilbene hybrid (GEM-STIL) was synthesized as a strategy to combine the well-known antioxidant activity of stilbenes with the reported antioxidant and anti-inflammatory actions of fibrates such as gemfibrozil. The physicochemical properties, including aqueous solubility, partition coefficient, chemical stability and enzymatic hydrolysis of GEM-STIL have been studied and indicated that it is stable and has a good lipophilicity. The biological activity was also evaluated for its effect on C2C12 cell line viability and antioxidant activities. Results: The results indicated that GEM-STIL was well tolerated and induced a reduction of cell viability only at higher concentration (100 μg/ml). On the other hand, also at lower nontoxic concentrations (5, 25 and 50 μg/ml) exhibited a significant reduction of ROS production as well as a protective effect against the induced oxidative stimulus. Conclusion: These findings suggest that GEM-STIL is a potential new antioxidant agent useful in oxidative stress-related pathologies.