798-96-9

Basic information

• Product Name: Benzoic acid, 4-(2,4-dinitrophenoxy)-, methyl ester
• CAS NO: 798-96-9
• Molecular Formula: C14H10N2O7
• Molecular Weight: 318.243
• Mol File: 798-96-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-(2,4-dinitrophenoxy)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-(2,4-dinitrophenoxy)-, methyl ester(798-96-9)
• EPA Substance Registry System: Benzoic acid, 4-(2,4-dinitrophenoxy)-, methyl ester(798-96-9)

Safety Data

• Hazardous Substances Data: 798-96-9(Hazardous Substances Data)

Upstream product

• 51-28-5 2,4-Dinitrophenol 
• 99-76-3 methyl 4-hydroxylbenzoate 
• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 70-34-8 2,4-Dinitrofluorobenzene 

Downstream Products

• 4096-88-2 1-azido-2,4-dinitrobenzene 

Relevant articles and documents

Kinetic study on SNAr reactions of 1-(Y-substituted-phenoxy)-2,4-dinitrobenzenes with Azide ion: Effect of changing nucleophile from hydroxide to Azide ion on reaction mechanism and reactivity

Second-order rate constants (kN3-) for SNAr reactions of 1-(Y-substituted-phenoxy)-2,4-dinitrobenzenes (2a-2h) with (Formula presented.) in 80 mol % H2O/20 mol % DMSO at 25.0 ± 0.1 °C have been measured spectrophotometrically. The Bronsted-type plot is linear with β1g=-0.38. The Hammett plots correlated with (Formula presented.) constants exhibit highly scattered points. In contrast, the Yukawa-Tsuno plot results in an excellent linear correlation with ρY = 1.02 and r = 0.51, indicating that a negative charge develops partially on the O atom of the leaving Y-substituted-phenoxy moiety in the transition state. Accordingly, the reactions have been concluded to proceed through a stepwise mechanism, in which expulsion of the leaving group occurs in the rate-determining step. Comparison of kN3- with the kOH- values reported previously for the corresponding reactions with OH has revealed that (Formula presented.) is only 6- to 26-fold than OH toward substrates 2a-2h, although the former is over 11 pKa units less basic than the latter. Solvation and polarizability effects have been suggested to be responsible for the unusual reactivity shown by (Formula presented.) and OH. Effects of changing nucleophile from OH to (Formula presented) on reaction mechanism and reactivity are discussed in detail.