79839-29-5Relevant articles and documents
Synthesis and characterization of bradykinin B2 receptor agonists containing constrained dipeptide mimics
Amblard, Muriel,Daffix, Isabelle,Bergé, Gilbert,Calmès, Monique,Dodey, Pierre,Pruneau, Didier,Paquet, Jean-Luc,Luccarini, Jean-Michel,Bélichard, Pierre,Martinez, Jean
, p. 4193 - 4201 (2007/10/03)
We have previously shown that substitution of the D-Tic-Oic dipeptide by a (3S)-[amino]-5-(carbonylmethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one (D-BT) moiety in the bradykinin B2 receptor antagonist HOE 140 resulted in a full potent and sel