79847-79-3

Upstream product

• 153946-46-4 (4R,5S,2'S)-4-cyclohexyl-1,5-dimethyl-3-(2-methyldecanoyl)imidazolidin-2-one 

Downstream Products

• 67253-77-4 (2S,3S,7S)-3,7-dimethylpentadecan-2-yl propionate 
• 1413919-15-9 (2S,6S)-2,6-dimethyl-1,1-dimethoxytetradecane 
• 79847-80-6 (S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (S)-2-methyl-decyl ester 
• 79847-83-9 (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (S)-2-methyl-decyl ester 

Relevant academic research and scientific papers

Ephedrine-Derived Imidazolidin-2-ones. Broad Utility Chiral Auxiliaries in Asymmetric Synthesis

The scope of the readily available (4R,5S)-1,5-dimethyl-4-phenylimidazolidin-2-one (4) and its 4-cyclohexyl analogue 6 as practical, efficient chiral auxiliaries has been demonstrated.The enolate chemistry of their N-acyl derivatives exhibits features which recommend their use in asymmetric synthesis.The stereoselective boron-mediated aldol as well as alkylation and acylation results are presented.The steric control benefit derived by conversion of phenyl to cyclohexyl is highlighted. - Key Words: Imidazolidin-2-one, (4R,5S)-1,5-dimethyl-5-phenyl- or cyclohexyl- / (-)-Ephedrine / Stereoselective aldol / alkylation, acylation