798544-31-7

Usage

Uses

Used in Pharmaceutical Preparations:
Octyl-POE is used as a solubilizing agent for improving the solubility of various substances in pharmaceutical formulations. This helps in the development of more effective and stable drug products.
Used in Personal Care Products:
In the personal care industry, Octyl-POE is used as an emulsifier and surfactant in products like lotions and creams. Its ability to mix oil and water components allows for the creation of stable emulsions, which are essential for the texture and performance of these products.
Used in Spermicides:
Octyl-POE is used as an active ingredient in spermicides, where it acts as a surfactant to disrupt the cell membranes of sperm, thereby preventing fertilization. Its surfactant properties make it an effective contraceptive option when used correctly.
However, it is important to note that the use of Octyl-POE in these applications is subject to regulatory guidelines and safety assessments due to the potential for irritation and toxicity. Manufacturers and formulators must ensure that the concentrations used are within safe limits to minimize any adverse effects on users.

Upstream product

• 75-21-8 oxirane 
• 111-87-5 octanol 
• 19327-37-8 diethylene glycol octyl ether 
• 19327-38-9 triethylene glycol monooctyl ether 
• 872-05-9 1-Decene 
• 124-18-5 decane 
• 112-30-1 1-Decanol 
• 1427511-80-5 4-tert-butyl-1,1-bis(decylperoxy)cyclohexane 
• 2050-77-3 Iododecane 
• 16623-96-4 (cyclododecylidene)bishydroperoxide 
• 107-21-1 ethylene glycol 
• 111-83-1 1-bromo-octane 
• 4359-57-3 2-heptyl-1,3-dioxolane 
• 93541-24-3 Aethylenglykol-octylaether-benzylaether 

Downstream Products

• 93541-24-3 Aethylenglykol-octylaether-benzylaether 
• 63632-58-6 2-(octyloxy)acetic acid 

Relevant academic research and scientific papers

Efficient concrete foam stabilizer and preparation method thereof

The invention discloses an efficient concrete foam stabilizer and a preparation method thereof, according to the efficient foam stabilizer, polyol is subjected to an esterification reaction to form ester bonds, and the ester bonds are connected with amphiphilic side chains, and the number of the amphiphilic side chains is 3-7; one end of the amphiphilic side chain is a hydrophobic chain segment, and the other end of the amphiphilic side chain is a hydrophilic unit; wherein the hydrophobic chain segment is an alkyl chain (R) with 8-14 carbons, and the hydrophilic unit is 2-10 ethylene oxide units. The efficient concrete foam stabilizer is a multi-chain type surfactant, and the multi-chain type surfactant is hydrolyzed under the alkaline condition to release an air-entraining type surfactant. The efficient concrete foam stabilizer has an excellent effect of stabilizing the air content of concrete, meanwhile, hardened concrete has a better pore structure, and the hardening strength of the concrete cannot be greatly influenced.

Nonionic Isatin Surfactants: Synthesis, Quantum Chemical Calculations, ADMET and Their Antimicrobial Activities

The most challenge task in the building up of surface-active molecules is maximizing their surface activity with good biological activity. A nonionic surfactant (N-isatin-EOm-Cn where m is 5, 7 and 9 ethylene glycol units and n is 8, 10 and 12) is achieved by first reacting isatin with chloroacetic acid and then with different types of ethoxylated (C8–C12) fatty alcohols that possess 5, 7 and 9 ethylene oxide units. The prepared surfactants were characterized by FTIR and 1H NMR to confirm the structure. The surface activity, biodegradability, antimicrobial, and antifungal activity of the surfactants were evaluated. In addition, quantum chemical calculations and computations of oral bioavailability were performed. The obtained data show that all the synthesized compounds had good surface activity, biodegradability and biological activity.

METHOD FOR PRODUCING FAT ALCOHOL ETHOXYLATES

The invention relates to a process for preparing fatty alcohol ethoxylates. According to the invention, the fatty alcohol ethoxylates are not obtained by means of the reaction of the fatty alcohols with ethylene oxide, as known from the prior art, but rat

Chemo- and Regioselective Functionalization of Polyols through Catalytic C(sp3)-C(sp3) Kumada-Type Coupling of Cyclic Sulfate Esters

This contribution describes a copper-catalyzed, C(sp3)-C(sp3) cross-coupling reaction of cyclic sulfate esters, a distinct class of electrophilic derivatives of polyols, with alkyl Grignard reagents to afford functionalized alcohol products in good yields. The method is operationally simple and highlights the potential of cyclic sulfate esters as highly reactive substrates in catalytic, chemoselective polyol transformations.

Highly efficient synthesis of monodisperse poly(ethylene glycols) and derivatives through macrocyclization of oligo(ethylene glycols)

A macrocyclic sulfate (MCS)-based approach to monodisperse poly(ethylene glycols) (M-PEGs) and their monofunctionalized derivatives has been developed. Macrocyclization of oligo(ethylene glycols) (OEGs) provides MCS (up to a 62-membered macrocycle) as versatile precursors for a range of monofunctionalized M-PEGs. Through iterative nucleophilic ring-opening reactions of MCS without performing group protection and activation, a series of M-PEGs, including the unprecedented 64-mer (2850Da), can be readily prepared. Synthetic simplicity coupled with versatility of this new strategy may pave the way for broader applications of M-PEGs. Macrocycles make synthesis easier: Convenient macrocyclization of the OEGs provides versatile macrocyclic sulfates. These compounds are cornerstones for both monofunctionalization of OEGs and highly efficient synthesis of monodisperse PEGs and derivatives, including an unprecedented 64-mer.

METHOD FOR PREPARING GLYCEROL ETHER AND GLYCOL ETHER

The present invention concerns a method for preparing glycerol ether or glycol ether comprising the reaction of a compound of formula (II) with a compound of formula (III) in the presence of a heterogeneous acid catalyst of formulas (II) and (III).

β-Carotene: A green, inexpensive, and convenient solvatochromic probe for the determination of solvent polarizability

Solvent polarizability has been previously determined by using the solvatochromic probe 3,20-di-tert-butyl-2,2,21,21-tetramethyl-3,5,7,9,11,13,15, 17,19-docosanonaene whose synthesis involves 15 steps. We show here that the natural dye β-carotene, 1,1′-(3,7,12,16-tetramethyl-1,3,5,7,9,11,13, 15,17-octadecanonaene-1,18-diyl)bis[2,6,6-trimethylcyclohexene], can be conveniently employed for the accurate determination of the same solvent property. This conclusion is based on both theoretical calculations and experimental data. The former includes free energies of solvation, and the wavenumber of the longest wavelength (i.e., the solvatochromic) transition. Both quantities for β-carotene correlate linearly with the corresponding values of the docosanonaene, with slopes and correlation coefficients of practically unity. The plot of experimentally calculated solvent polarizability of β-carotene versus that of the docosanonaene was found to be linear for 68 solvents. Previously unknown solvent polarizability values are reported for eight ROCH2CH2OH (R = C1 to C10) and four 1-allyl-3-R-imidazolium chloride ionic liquids (R = C6 to C10). The dependence of solvent polarizability on the number of carbon atoms in the hydrocarbon chains of several classes of solvents is calculated, it shows the importance of van der Waals interactions in ionic liquids.

Synthesis of alkyl hydroperoxides via alkylation of gem -dihydroperoxides

2-Fold alkylation of 1,1-dihydroperoxides, followed by hydrolysis of the resulting bisperoxyacetals, provides a convenient method for synthesis of primary and secondary alkyl hydroperoxides.

Synthesis of isoprenoid chain-contained chemical probes for an investigation of molecular interactions by using quartz crystal microbalance

Five probes including four that contained isoprenoid chain were synthesized. These probes were assembled onto the gold-coated quartz crystal chips for analysis of their interactions with four yeast proteins by using the quartz crystal microbalance technology. Results showed that 3-phosphoglycerate phosphokinase and triosephosphate isomerase had clear interactions with certain probes, while glutathione reductase and phosphoglucose isomerase gave much lower interaction signals. It also suggested that 3-phosphoglycerate phosphokinase had two sites interacting with the probe attached with a geranyl moiety. Further molecule simulation experiments provided supportive information on these intermolecular interactions. Together, our data suggested that there are hydrophobic interactions, with relatively good selectivity, between isoprenoid chain and proteins.

Highly efficient stereoselective catalytic C(sp3)-H insertions with donor rhodium carbenoids generated from cyclopropenes

Rings of five and six: Donor alkenyl rhodium carbenoids generated from 3,3-dimethylcyclopropenylcarbinols exhibit high reactivity in intramolecular C-H insertions. The reactions proceed under remarkably mild conditions, tolerate the presence of the free hydroxy group, and afford an efficient and stereoselective access to a variety of functionalized carbocycles and oxygen heterocycles. Copyright