798554-60-6

Upstream product

• 114817-96-8 (4S,5R)-2,2-dimethyl-4-hydroxymethyl-5-vinyl-1,3-dioxolane 
• 990-91-0 dibenzyl [[bis(benzyloxy)phosphoryl]oxy]phosphonate 
• 58645-35-5 3,4-O-isopropylidine L-arabinopyranose 
• 213767-09-0 2,3-O-isopropylidene-L-erythrofuranose 
• 676-58-4 methylmagnesium chloride 

Downstream Products

• 798554-54-8 Phosphoric acid (4S,5S)-5-acetyl-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester dibenzyl ester 

Relevant academic research and scientific papers

Substrate analogs for the investigation of deoxyxylulose 5-phosphate reductoisomerase inhibition: Synthesis and evaluation

Deoxyxylulose 5-phosphate (DXP) analogs were synthesized and evaluated as alternative substrates and inhibitors of recombinant Synechocystis PCC6803 DXP reductoisomerase (DXR; EC 1.1.1.267). Five of the compounds tested (1,2-dideoxy-d-threo-3-hexulose 6-phosphate, 1-deoxy-l-ribulose 5-phosphate, 2S,3R-dihydroxybutyramide 4-phosphate, 4S-hydroxypentan-2-one 5-phosphate, and 3S-hydroxypentan-2-one 5-phosphate) acted as relatively weak competitive inhibitors when compared to fosmidomycin. A sixth compound, 3R,4S-dihydroxy-5- oxohexylphosphonic acid, served as an alternate substrate, as has recently been reported for the same compound with Escherichia coli DXR.