79858-48-3 Usage
Uses
Used in Scientific Research:
1-Benzyl-1,2,3,6-tetrahydropyridine-4-carboxylic acid is used as a neurotoxin in the creation of animal models for Parkinson's disease research. It is utilized for [application reason] because it selectively destroys dopamine-producing neurons in the brain, leading to a significant reduction in dopamine levels and the manifestation of motor deficits that are characteristic of Parkinson's disease.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 1-Benzyl-1,2,3,6-tetrahydropyridine-4-carboxylic acid is used as a tool compound for the development and testing of drugs aimed at treating Parkinson's disease. Its ability to mimic the disease's symptoms allows researchers to assess the efficacy of potential treatments in a controlled environment.
Safety Considerations:
Due to its hazardous nature and toxic effects, 1-Benzyl-1,2,3,6-tetrahydropyridine-4-carboxylic acid must be handled with extreme caution in laboratory settings to prevent accidental exposure and ensure the safety of researchers and the integrity of the experimental conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 79858-48-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,8,5 and 8 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 79858-48:
(7*7)+(6*9)+(5*8)+(4*5)+(3*8)+(2*4)+(1*8)=203
203 % 10 = 3
So 79858-48-3 is a valid CAS Registry Number.
InChI:InChI=1/C13H15NO2/c15-13(16)12-6-8-14(9-7-12)10-11-4-2-1-3-5-11/h1-6H,7-10H2,(H,15,16)
79858-48-3Relevant academic research and scientific papers
An efficient synthesis of N-alkyl-4-substituted 3H-pyridine-2,6-dione. Synthesis of isoguvacine and MDL-11,939
Chang, Meng-Yang,Chen, Shui-Tein,Chang, Nein-Chen
, p. 2321 - 2334 (2007/10/03)
An efficient route towards the synthesis of N-alkyl-4-substituted 3H-pyridine-2,6-dione using various N-alkyl-α-sulfonylacetamides and two α,β-unsaturated esters as starting materials is described. Isoguvacine and MDL-11,939 with have potential biological activities were synthesized via this strategy.
