79866-78-7

Usage

Structure

A derivative of the triazole ring with a phenyl group and an aldehyde functional group.

Applications

Potential use in organic synthesis and materials science.

Reactivity

Exhibits unique reactivity due to the presence of the triazole ring and the aldehyde group.

Chemical transformations

Useful for various chemical transformations and reactions.

Building block

Valuable building block for the synthesis of diverse organic compounds and materials.

Potential applications

Pharmaceutical, agrochemical, and materials science.

Aromatic nature

Has an aromatic nature due to the presence of the phenyl group.

Functionalization

Potential for further functionalization, making it a versatile compound in organic chemistry.

Upstream product

• 2579-22-8 Phenylpropargyl aldehyde 
• 622-37-7 Phenyl azide 
• 104-55-2 3-phenyl-propenal 

Downstream Products

• 79866-73-2 5-[(Z)-2-(1,5-Diphenyl-1H-[1,2,3]triazol-4-yl)-vinyl]-1-phenyl-1H-tetrazole 
• 134926-80-0 [1-(1,5-Diphenyl-1H-[1,2,3]triazol-4-yl)-meth-(E)-ylidene]-ethyl-amine 
• 134926-81-1 [1-(1,5-Diphenyl-1H-[1,2,3]triazol-4-yl)-meth-(E)-ylidene]-isopropyl-amine 
• 134926-82-2 tert-Butyl-[1-(1,5-diphenyl-1H-[1,2,3]triazol-4-yl)-meth-(E)-ylidene]-amine 
• 134926-79-7 [1-(1,5-Diphenyl-1H-[1,2,3]triazol-4-yl)-meth-(E)-ylidene]-methyl-amine 
• 134926-83-3 Benzyl-[1-(1,5-diphenyl-1H-[1,2,3]triazol-4-yl)-meth-(E)-ylidene]-amine 
• 98013-39-9 4-benzoyl-1-(tert-butyl)-1,2,3-triazole 
• 74731-42-3 (1-benzyl-1H-1,2,3-triazol-4-yl)(phenyl)methanone 
• 118526-76-4 (1-Methyl-1H-[1,2,3]triazol-4-yl)-phenyl-methanone 
• 134926-96-8 4-benzoyl-1-ethyl-1,2,3-triazole 
• 134926-97-9 4-benzoyl-1-isopropyl-1,2,3-triazole 

Relevant academic research and scientific papers

Lewis base catalyzed aerobic oxidative intermolecular azide-zwitterion cycloaddition

The discovery of a novel aerobic oxidative intermolecular azide-zwitterion reaction catalyzed by an organocatalyst is presented. It is demonstrated that the merger of the Lewis base 1,8-diazabicyclo[5.4.0]undec-7-ene and electrondeficient olefins generates reactive zwitterion intermediates, which readily participate in cycloaddition reactions with an array of azides, thus providing facile entry to fully or highly substituted 1,2,3-triazole frameworks. The reaction features an excellent substrate scope, and the products are obtained with high yields and excellent regioselectivities. It is demonstrated that some of these products can be transformed into pharmaceutically important agents. In addition to the experimental results, a detailed mechanistic survey is also provided, including MS studies rationalizing the origin of regioselective control.

Cycloaddition of organic azides to α,β-acetylenic aldimines

The reaction selectivity of aryl azides with α,β-acetylenic aldimines R1C≡C-CH=NR2 is independent of R1 and R2: the addition always occurs chemospecifically at the triple bond and results in formation of 1-aryl-