79868-64-7

Upstream product

• 5445-17-0 Methyl 2-bromopropionate 
• 104-55-2 3-phenyl-propenal 
• 186581-53-3 diazomethane 
• 14371-10-9 (E)-3-phenylpropenal 
• 67498-12-8 (E)-(2S,3S)-3-Hydroxy-2-methyl-5-phenyl-pent-4-enoic acid methyl ester 
• 292638-85-8 acrylic acid methyl ester 
• 86853-06-7 Methyl 2-methyl-3-oxo-5-phenyl-4-pentenoate 
• 5634-52-6 1,1-dimethoxy-propene 

Downstream Products

• 86853-06-7 Methyl 2-methyl-3-oxo-5-phenyl-4-pentenoate 
• 82414-51-5 (E)-(2R,3S)-2-Methyl-5-phenyl-pent-4-ene-1,3-diol 
• 82414-48-0 (E)-(2S,3R)-3-Methoxy-2-methyl-5-phenyl-pent-4-enoic acid 
• 82414-47-9 (E)-(2S,3R)-3-Methoxy-2-methyl-5-phenyl-pent-4-enoic acid methyl ester 
• 82414-51-5 (E)-(2S,3S)-2-Methyl-5-phenyl-pent-4-ene-1,3-diol 
• 67498-12-8 (E)-syn-methyl 3-hydroxy-2-methyl-5-phenyl-4-pentanoate 
• 88155-83-3 methyl (E)-(3R^*,4S^*)-4-methoxy-3-methyl-6-phenylhexa-5-enoate 
• 73341-71-6 (+/-)-oudemansin A 
• 73341-71-6 oudemansin A 
• 107184-56-5 (E)-(2S,3R)-3-Acetoxy-2-methyl-5-phenyl-pent-4-enoic acid methyl ester 
• 92979-24-3 (2R,3R)-2,4-Bis-benzyloxy-3-methyl-butyraldehyde 
• 92979-25-4 (2R,3R)-2,4-Bis-benzyloxy-3-methyl-butan-1-ol 
• 92979-23-2 C₂₆H₂₈O₂ 

Relevant academic research and scientific papers

Generation of (E)-Silylketene acetals in a Rhodium-DuPhos catalyzed two-step reductive aldol reaction

(equation presented) Mechanistic studies employing in situ NMR analysis implicate intermediate silicon enolates as reactive intermediates in the Rh-DuPhos catalyzed two-step reductive aldol reaction with Cl2MeSiH. These enolates undergo noncata

Spontaneous aldol and Michael additions of simple enoxytrimethylsilanes in DMSO

Activation of simple trimethylsilyl ketene acetals by dipolar aprotic solvents has been evidenced, allowing efficient solvent assisted aldol and Michael additions under extremely simple, mild and metal free conditions. (C) 2000 Elsevier Science Ltd.

Reformatsky-type addition of esters of α-halogeno carboxylic acids to aldehydes and ketones in the presence of Fe(CO)5

Reformatsky-type addition of esters of α-halogeno carboxylic acids to aldehydes and ketones in the presence of Fe(CO)5 and an activating agent (CBrCl3 or I2) afforded the corresponding esters of β-hydroxy acids in good yields. Possible reaction mechanisms are discussed.

Cobalt(II) Catalyzed Coupling Reaction of α,β-Unsaturated Compounds with Aldehydes by the Use of Phenylsilane. New Method for Preparation of β-Hydroxy Nitriles, Amides, and Esters

A new crossed coupling reaction of α,β-unsaturated nitriles with aldehydes was performed by using phenylsilane and a catalytic amount of bis(1,3-diketonato)cobalt(II) to give β-siloxy nitriles in good yields.Similarly, α,β-unsaturated amides and esters also reacted under the same conditions to afford β-siloxy amides or esters.The present reaction provides a new and facile method for preparation of β-hydroxy nitriles, amides, and esters.

LIPASE CATALYZED ENANTIOSELECTIVE HYDROLYSIS OF 2-METHYL 3-ACETOXY ESTERS

Highly enantioselective hydrolyses of syn-3-acetoxy-2-methyl ester and anti-3-acetoxy-2-methyl esters with lipase "Amano A" and lipase "Amano A-6" isolated from Aspergillus niger, are described.

STEREOSELECTIVE ADDITIONS TO CARBOXYLIC ACID DIANIONS AND β-LACTONE SUBSTITUTED ESTER ENOLATES. APPLICATION TO THE SYNTHESIS OF RACEMIC EPI-BLASTMYCINONE, δ-MULTISTRIATINE, PARACONIC ESTERS AND LIGNANTYPE DILACTONES

New stereoselective syntheses are reported for racemic 4-epi-blastmycinone (6) and δ-multistriatine (13) utilizing the anti-configurated γ,δ-unsaturated β-hydroxy-carboxylic acids 2a/b.A diastereo- and enantioselective aldoltype addition of phenylacetic acid dianion to benzaldehyde has been achaived by employing optically active alkoxide amide bases.Finally, highly stereocontrolled additions to the novel β-lactone substituted ester enolates 22 are described.