79892-12-9Relevant academic research and scientific papers
PYRROLES FROM KETOXIMES AND ACETYLENE
Trofimov, B. A.,Mikhaleva, A. I.,Polovnikova, R. I.,Korostova, S. E.,Nesterenko, R. N.,et al.
, p. 783 - 786 (1981)
2-(2-Furyl)pyrroles and 1-vinyl-2-(2-furyl)pyrroles were obtained in up to 80percent yields in the reaction of ketoximes of the furan series with acetylene in MOH-dimethyl sulfixide (M = Li, K) superbase media.
NUCLEOPHILIC ADDITION TO ALKYNES IN SUPERBASIC CATALYTIC SYSTEMS. V. VINYLATION OF KETOXIMES
Tarasova, O. A.,Korostova, S. E.,Mikhaleva, A. I.,Sobenina, L. N.,Nesterenko, R. N.,et al.
, p. 863 - 869 (2007/10/02)
The nucleophilic addition of the oximes of aliphatic, aromatic, and heteroaromatic ketones to acetylene in the superbasic heterophase potassium hydroxide-DMSO system was studied.The vinylation of ketoximes not containing a CH2 group at the α position to the oxime function goes well, and the yields of the O-vinyloximes are 38-72percent.With such a group and with electronegative substituents in the aromatic ring of the ketoxime rapid heterocyclization of the O-vinyloximes occurs under the reaction conditions, giving the corresponding 2-substituted pyrroles.
PYRROLES ROM KETOXIMES AND ACETYLENE. 40. REACTION OF ALKYL HETARYL KETOXIMES WITH 1,2-DICHLOROETHANE IN SUPERBASE MEDIA
Korostova, S. E.,Nesterenko, R. N.,Mikhaleva, A. I.,Polovnikova, R. I.,Golovanova, N. I.
, p. 749 - 754 (2007/10/02)
2-(2-Furyl)- and 2-(2-thienyl)pyrroles and their N-vinyl derivatives were synthesized by the reaction of alkyl furyl (thienyl) ketoximes with 1,2-dichloroethane in superbase media. 2-Chloroethyl and vinyl ethers of alkyl hetaryl ketoximes are intermediates in the reaction.
