79892-85-6

Usage

InChI:InChI=1/C9H6N2O4/c10-7-4-5-3-6(11(13)14)1-2-8(5)15-9(7)12/h1-4H,10H2

Upstream product

• 205239-08-3 (6-nitro-2-oxo-2H-chromen-3-yl)carbamic acid tert-butyl ester 
• 97-51-8 5-Nitrosalicylaldehyde 
• 10242-15-6 6-nitro-2-oxo-2H-chromen-3-carboxylic acid 
• 787-63-3 3-acetamido-6-nitro-2H-chromen-2-one 

Downstream Products

• 1372879-67-8 C₂₄H₁₉BrN₂O₅ 

Relevant academic research and scientific papers

Hydrolysis-free synthesis of 3-aminocoumarins

A commonly encountered problem in the synthesis of 3-aminocoumarins is the formation of 3-hydroxycoumarins. A solution to this problem, which involves non-aqueous formation of the 3-aminocoumarin system, is described.

An efficient and facile synthesis of substituted 3-aminocoumarins under mw irradiation in dry media

A variety of 3-aminocoumarins were prepared by reaction of salicylaldehyde derivatives with benzoylglycine catalyzed by piperidine under microwave irradiation (MWI) and subsequent acid hydrolysis. The structure of products was proven by elemental analysis, IR, NMR and Mass spectra. These investigations will contribute to development of environmentally friendly and inexpensive processes in organic synthesis.

Synthesis of substituted 3-aminocoumarins from ethyl N-2- hydroxyarylideneglycinates

3-Aminocoumarin and its derivatives are prepared by a thermal (150- 170°C) conversion reaction on the corresponding ethyl N-2- hydroxyarylideneglycinates,[2-HOC6H3(X)CH=NCH2CO2C2Hs; X = H, 5-Br, 5- OH, 5-NO2, 3-OMe, 4-OMe, and 5,6-benzo], which are synthesized by condensing ethyl glycinate hydrochloride with substituted salicylaldehyde.

Synthesis of new 2H,4H-benzopyrano[3,4-b]pyridine-1,3,5-trione derivatives via carbon suboxide

The new 2H,4H-[1]benzopyrano[3,4-b]pyridine-1,3,5-trione derivatives 10a-f were prepared in the following three steps; the first preparation of new N-(tert-butoxycarbonyl)-3-amino-2H-1-benzopyran-2-one derivatives 5a-f by reaction of coumarin-3-carboxylic acids and diphenylphosphorlyazide, then hydrolysis of 5a-f with gaseous hydrogen chloride to give the corresponding amines 7a-f, and finally the preparation of 10a-f by reaction of 7a-f and carbon suboxide in the presence of a Lewis acid.

(2-Oxo-2H-1-benzopyran-3-yl)aminooxoacetic acids and their derivatives

The present invention relates to (2-oxo-2H-1-benzopyran-3-yl)aminooxoacetic acids and their derivatives having the following structural formula: STR1 wherein R1 is hydrogen, halogen, hydroxy, lower alkoxy, lower alkyl or nitro and R2 is hydrogen or lower alkyl and their pharmaceutically acceptable salts thereof; these compounds are indicated in the management of allergic manifestations such as, for example, asthma, hay fever and the like. The present invention relates to (2-oxo-2H-1-benzopyran-3-yl)aminooxoacetic acids and their derivatives having the following structural formula: STR2 wherein R1 is hydrogen, halogen, hydroxy, lower alkoxy, lower alkyl or nitro. R2 is hydrogen or lower alkyl and their pharmaceutically acceptable salts thereof.