799-13-3

Usage

+ Color

Colorless to pale yellow solid

+ Odor

Slight odor

+ Solubility

Insoluble in water, soluble in organic solvents

+ Molecular Weight

324.45 g/mol

+ Functional Groups

Hydroxyl (-OH) and tert-butyl (-OC(CH3)3) groups

Uses

+ Personal care products
+ UV filter in sunscreens

Functionality

+ Absorbs and dissipates ultraviolet (UV) radiation
+ Protects skin from harmful effects such as sunburn and skin cancer

Concerns

+ Potential to disrupt hormone function
+ Environmental impact
+ Regulated use in some regions
+ Ongoing research to understand potential effects on human health and the environment.

Upstream product

• 50-00-0 formaldehyd 
• 98-54-4 para-tert-butylphenol 
• 6638-87-5 4-(tert-butyl)-2-(hydroxymethyl)phenol 
• 14362-12-0 2,2'-methylenebis(4,6-di-tert-butylphenol) 
• 801-19-4 3-Chlor-2,2'-dihydroxy-5,5'-di-tert-butyl-diphenylmethan 
• 96-76-4 2,4-di-tert-Butylphenol 
• 2725-53-3 2-hydroxy-5-t-butylbenzaldehyde 
• 16396-75-1 5-Chlor-4-hydroxy-3-hydroxymethyl-1-tert.-butyl-benzol 

Downstream Products

• 1264-58-0 4-(tert-butyl)-2,6-bis{{5-(tert-butyl)-3-{[5-(tert-butyl)-2-hydroxyphenyl]methyl}-2-hydroxyphenyl}methyl}phenol 
• 1756-93-0 bis-{5-tert-butyl-3-[5-tert-butyl-3-(5-tert-butyl-2-hydroxy-benzyl)-2-hydroxy-benzyl]-2-hydroxy-phenyl}-methane 
• 98085-84-8 2,2'-Dimethoxy-5,5'-di-tert-butyldiphenylmethane 
• 149790-47-6 Acetic acid 2-(2-acetoxy-5-tert-butyl-benzyl)-4-tert-butyl-phenyl ester 
• 197652-87-2 2',2''-dihydroxy-3',3''-bis-(2'''-hydroxy-5'''-tert-butylbenzyl)-5',5''-di-tert-butyl-4-formyltriphenylmethane 
• 57693-37-5 2,2'-methylenebis(6-bromo-4-t-butylphenol) 
• 165318-85-4 6,6'-bis(bromomethyl)-4,4'-di-tert-butyl-2,2'-methanediyldiphenol 
• 737792-54-0 (5-tert-butyl-2-hydroxyphenyl)-(5-tert-butyl-2-methoxyphenyl)methane 
• 737792-43-7 4,4-bis-{3-[4-tert-butyl-2-(5-tert-butyl-2-methoxy-benzyl)-phenoxy]-propyl}-4H-cyclopenta[2,1-b;3,4-b']dithiophene 
• 25446-98-4 2,2'-dihydroxy-5,5'-di-tert-butylbenzophenone 
• 149826-78-8 4-t-butyl-2-(5-t-butyl-3-chloromethylsalicyloyl)-6-chloromethylphenol 
• 149790-52-3 Acetic acid 2-(2-acetoxy-5-tert-butyl-benzoyl)-4-tert-butyl-phenyl ester 
• 149790-66-9 2-bromo-4-t-butyl-6-<5-t-butyl-3-<5-t-butyl-3-(5-t-butylsalicyloyl)salicyl>salicyloyl>phenol 
• 149790-91-0 4-t-butyl-2-<5-t-butyl-3-<5-t-butyl-3-(5-t-butylsalicyl)salicyloyl>salicyl>phenol 

Relevant academic research and scientific papers

Synthesis of Monofunctionalized Calix[5]arenes

Seven OH-free and O -permethylated monofunctionalized calix[5]arenes carrying either additional methyl or tert -butyl groups are prepared following fragment condensation protocols. This strategy proves to be superior to previous approaches. Calix[5]arenes with free OH groups all adopt a cone conformation stabilized by a seam of hydrogen bonds at the lower rim. Post-condensation modifications, i.e., methylation of phenolic OH groups or functional group interconversions can also be achieved. Bulky tert -butyl groups are also found to stabilize the cone conformations of O -methylated compounds. These compounds offer versatile functional groups that make these concave molecules interesting building blocks for the synthesis of more sophisticated molecular architectures.

Interaction between biphenols and anions: Selective receptor for dihydrogenphosphate

Biphenol was shown to bind dihydrogenphosphate (H2PO 4-) selectively over various other anions (MeCO 2-, Cl-, Br-, I-, NO 3-, HSO4-). The highly selectivity of biphenol toward dihydrogenphosphate is explained in terms of the basicity and shape of the guest anion.

Calix[4]arene-functionalized poly-cyclopenta[2,1-b;3,4-b′] bithioplienes with good recognition ability and selectivity for small organic molecules for application in QCM-based sensors

Some C2v symmetric cyclopenta[2,1-b;3,4-b′]bithiophenes differently substituted at the 4 position with a calix[4]arene group were synthesized and electrochemically polymerized by anodic coupling. The polymers were characterized by cyclic voltam

Syntheses and properties of a new type of Lewis acids incorporating linked bisphenoxide moiety

Several ligands for a new type of Lewis acid, which incorporates two linked phenols, were synthesized and the reaction of these ligands with trimethylaluminum quantitatively gave Lewis acids. These Lewis acids were found to be an efficient promoter for the rearrangement of epoxides to carbonyl compounds as well as a useful protector of acetophenone against hydride-reduction. The VT-NMR spectrum and NOESY spectrum of a 1:1 complex of Lewis acid 2a (methyl[2,2′-(m-xylene-α,α′-diyl)bis(4,6-di-t- butylphenoxido)aluminum and acetophenone provided data on the structure of a complex of acetophenone and 2a.

Metal-template ortho-regioselective mono- and bis-de-tert-butylation of poly-tert-butylated phenols

A metal-template ortho-regioselective mono- and bis-de-tert-butylation of poly-tert-butylated phenol-formaldehyde oligomers is reported.