79918-73-3Relevant academic research and scientific papers
Asymmetric reduction of enones with Synechococcus sp. PCC 7942
Shimoda, Kei,Kubota, Naoji,Hamada, Hiroki,Kaji, Misato,Hirata, Toshifumi
, p. 1677 - 1679 (2004)
Synechococcus sp. PCC 7942, a cyanobacterium, reduced both the endocyclic C-C double bond of s-trans enones and the exocyclic C-C double bond of s-cis enones with high enantioselectivity to afford the corresponding (S)-ketones under illumination.
Asymmetric transformation of enones with Synechococcus sp. PCC 7942
Shimoda, Kei,Kubota, Naoji,Hamada, Hiroki,Yamane, Shin-Ya,Hirata, Toshifumi
, p. 2269 - 2272 (2007/10/03)
Asymmetric transformation of enones was investigated with cultured cells of Synechococcus sp. PCC 7942 (a cyanobacterium). The cells reduced both the endocyclic C-C double bond of s-trans enones and the exocyclic C-C double bond of s-cis enones with high enantioselectivity to afford optically active α-substituted (S)-ketones under illumination. In addition, the reduction of the double bond of these enones was accompanied by the formation of saturated alcohols. The cells preferentially reduced simple aliphatic ketones rather than cyclic ones to the corresponding (S)-alcohols with excellent enantioselectivity.
Microbiological Reduction of α,β-Unsaturated Ketones by Beauveria sulfurescens
Kergomard, A.,Renard, M. F.,Veschambre, H.
, p. 792 - 798 (2007/10/02)
Microbiological reduction of α,β-unsaturated ketones was studied.Variously substituted cyclopentenones, cyclohexenones, and methylalkenones were reduced by Beauveria sulfurescens under low-aeration conditions.The reaction takes place only with a small substituent in the α-position and hydrogen in the β-position.The saturated ketone is always obtained, sometimes accompanied by saturated alcohol.Yields and optical purities of the products are excellent.
