799246-07-4

Upstream product

• 88196-06-9 (1S,2S)-1-phenyl-1,2-propanediol 

Downstream Products

• 255060-78-7 (-)-(1R,2S)-1-azido-1-phenyl-2-propanol 
• 420087-33-8 (2R,3R)-2-methyl-3-phenylaziridine 
• 61091-40-5 (-)-trans-(2S,3S)-2-methyl-3-phenylaziridin 
• 51-64-9 dexamfetamine 
• 156-34-3 l-amphetamine 
• 167083-50-3 (1S,2R)-1-azido-1-phenylpropane-2-ol 
• 2323-36-6 SELEGILINE 
• 33817-09-3 (R)-2-methylamino-1-phenylpropane 

Relevant academic research and scientific papers

Asymmetric synthesis of l-DOPA and (R)-selegiline via, OsO 4-catalyzed asymmetric dihydroxylation

A simple and effective procedure for the enantioselective synthesis of two important neurotransmitter drugs, that is, (S)-3,4-dihydroxyphenylalanine (l-DOPA) and (R)-N,α-dimethyl-N-2-propynylbenzeneethaneamine [(R)-selegiline], is described by employing the Sharpless asymmetric dihydroxylation (AD) as a key step to introduce chirality.

Chemoenzymatic synthesis of chiral β-azidoalcohols. Application to the preparation of chiral aziridines and aminoalcohols

From the microbiological reduction of 3-azido-2-octanone, 3-azido-4-phenyl-2-butanone and 1-azido-1-phenyl-2-propanone, homochiral isomers of the corresponding β-azidoalcohols were prepared. These 'α-bichiral' synthons were used to prepare all the stereoi