799280-88-9

Upstream product

• 799281-04-2 Methanesulfonic acid (R)-1-[(3aR,5R,6R,6aR)-6-((R)-1-benzyloxymethyl-allyl)-6-hydroxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl]-2-methanesulfonyloxy-ethyl ester 
• 2847-00-9 1,2:5,6-di-O-isopropylidene-α-D-hexofuran-3-ulose 
• 210224-78-5 3-C-[(S)-1-carbomethoxy-prop-2-enyl]-1,2:5,6-di-O-isopropylidene-α-D-allofuranose 
• 799281-00-8 3-C-[(R)-1-hydroxymethyl-prop-2-enyl]-1,2:5,6-di-O-isopropylidene-α-D-allofuranose 
• 799280-87-8 3-C-[(R)-1-benzyloxymethyl-prop-2-enyl]-1,2:5,6-di-O-isopropylidene-α-D-allofuranose 
• 799281-02-0 3-C-[(R)-1-benzyloxymethyl-prop-2-enyl]-1,2-O-isopropylidene-α-D-allofuranose 
• 100-39-0 benzyl bromide 

Downstream Products

• 799280-94-7 (1R,3R,4R,5R,6R)-4,5-diacetoxy-6-benzyloxymethyl-3-(thymin-1-yl)-2-oxa-bicyclo[3.3.0]oct-7-ene 
• 799280-89-0 (1R,2R,6R,8R,11R)-11-benzyloxymethyl-1-hydroxy-4,4-dimethyl-3,5,7-trioxatricyclo[6.3.0.0^2,6]undec-9-ene 

Relevant academic research and scientific papers

Diastereoselective Reformatsky reaction of methyl 4-bromocrotonate with 1,2:5,6-di-O-isopropylidene-α-D-ribo-hexofuranos-3-ulose: Application to novel bicyclic nucleosides

This paper describes an efficient synthetic route for novel bicyclic nucleosides. The stereochemistry of the targeted bicyclic nucleosides was successfully achieved by vinylogous Reformatsky reaction and ring closing metathesis reaction on a carbohydrate