79950-75-7

Upstream product

• 79950-65-5 N-[(1,1-dimethylethoxy)carbonyl]-3-[(phenylmethoxy)methyl]-L-histidine 
• 79950-77-9 N^α-tert-Boc-N^?-<(benzyloxy)methyl>-L-histidine methyl ester 
• 20898-43-5 4-(2-tert-butoxycarbonylamino-2-methoxycarbonyl-ethyl)-1H-imidazole-1-carboxylic acid tert-butyl ester 
• 4467-54-3 l-histidine methyl ester dihydrochloride 
• 79950-74-6 N(α)-t-butoxycarbonyl-N(?)-benzyloxymethyl-L-histidyl-L-phenylalanine methyl ester 

Downstream Products

• 79950-68-8 (S)-2-[(S)-2-(2-tert-Butoxycarbonylamino-acetylamino)-3-(1H-imidazol-4-yl)-propionylamino]-3-phenyl-propionic acid 
• 79950-73-5 (S)-2-[(S)-3-(3-Benzyloxymethyl-3H-imidazol-4-yl)-2-(2-tert-butoxycarbonylamino-acetylamino)-propionylamino]-3-phenyl-propionic acid 
• 79950-76-8 t-butoxycarbonylglycyl-N(?)-benzyloxymethyl-L-histidyl-L-phenylalanine methyl ester 

Relevant academic research and scientific papers

Protection of Histidine Side-chains with ?-Benzyloxymethyl- or ?-Bromobenzyloxymethyl-groups

N(α)-t-Butoxycarbonyl-N(?)-benzyloxymethyl-L-histidine (1) and N(α)-t-butoxycarbonyl-N(?)-4-bromobenzyloxymethyl-L-histidine (2) have been prepared and shown to be suitable derivatives for peptide synthesis with histidine; the synthetic intermediates had