79960-41-1Relevant academic research and scientific papers
Novel indolizino[8,7-b]indole hybrids as anti-small cell lung cancer agents: Regioselective modulation of topoisomerase II inhibitory and DNA crosslinking activities
Chang, Sue-Ming,Christian, Wilson,Wu, Ming-Hsi,Chen, Tai-Lin,Lin, Yi-Wen,Suen, Ching-Shu,Pidugu, Hima Bindu,Detroja, Dilip,Shah, Anamik,Hwang, Ming-Jing,Su, Tsann-Long,Lee, Te-Chang
, p. 235 - 249 (2017)
A novel series of bis(hydroxymethyl)indolizino[8,7-b]indole hybrids composed of β-carboline (topoisomerase I/II inhibition) and bis(hydroxymethyl)pyrrole (DNA cross-linking) are synthesized for antitumor evaluation. Of tumor cell lines tested, small cell
Reissert Compound Studies. XLII. Synthesis and Reactions of the 3,4-Dihydro-β-carboline Reissert Compound and Observations on α, β, and γ-Carbolines
Veeraraghavan, Seshardi,Popp, Frank D.
, p. 909 - 915 (2007/10/02)
3,4-Dihydro-β-carboline and benzo-γ-carboline yielded Reissert compounds.The 3,4-dihydro-β-carboline Reissert compound, through its acid- and base-promoted reactions, was found to be a very useful intermediate in the synthesis of several β-carboline de
