79972-52-4Relevant academic research and scientific papers
Reactions of Propargyl Alcohols with Amide Acetals
Parker, Kathlyn A.,Petraitis, Joseph J.,Kosley, Raymond W.,Buchwald, Stephen L.
, p. 389 - 398 (2007/10/02)
The reaction of a propargyl alcohol with an amide acetal affords enamine products, an allenic amide (a sigmatropic rearrangement product), or a product resulting from enamine formation followed by sigmatropic rearrangement.Subsequent procedures afforded α,β-unsaturated aldehydes, α-hydroxy ketones, β-keto amides, and spiro lactones.
