79984-63-7

Upstream product

• 108-24-7 acetic anhydride 
• 18312-46-4 (2-methoxyphenyl)hydrazine 
• 70638-42-5 2-(2-methoxy-phenylazo)-2,5-dimethyl-furan-3-one 
• 90-04-0 2-methoxy-phenylamine 

Downstream Products

• 1567335-45-8 5-(4-chlorophenyl)-1-(2-methoxyphenyl)-1H-pyrazol-3-yl trifluoromethanesulfonate 
• 1567335-46-9 5-(4-chlorophenyl)-1-(2-methoxyphenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 
• 1567335-23-2 5-(4-chlorophenyl)-1-(2-methoxyphenyl)-3-(2,2,5,5-tetramethyl-2,5-dihydrofuran-3-yl)-1H-pyrazole 
• 1567335-24-3 5-(4-chlorophenyl)-1-(2-methoxyphenyl)-3-(2,2,5,5-tetramethyltetrahydrofuran-3-yl)-1H-pyrazole 
• 1567335-44-7 5-(4-chlorophenyl)-1-(2-methoxyphenyl)-1H-pyrazol-3(2H)-one 
• 1567335-29-8 5-(4-chlorophenyl)-1-(2-methoxyphenyl)-3-(2,2,6,6-tetramethyltetrahydropyran-4-yl)-1H-pyrazole 
• 1567334-96-6 5-(4-chlorophenyl)-1-(2-methoxyphenyl)-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole 
• 1567402-64-5 5-(4-chlorophenyl)-1-(2-methoxyphenyl)-3-[(2,2,4,4-tetramethyloxetan-3-yl)methoxy]-1H-pyrazole 
• 1567402-47-4 5-(4-chlorophenyl)-1-(2-methoxyphenyl)-3-((2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)oxy)-1H-pyrazole 
• 1567402-49-6 5-(4-chlorophenyl)-1-(2-methoxyphenyl)-3-({1-[(1-methylethyl)sulfonyl]azetidin-3-yl}oxy)-1H-pyrazole 
• 1567402-50-9 5-(4-chlorophenyl)-1-(2-methoxyphenyl)-3-{[1-(methylsulfonyl)azetidin-3-yl]oxy}-1H-pyrazole 
• 1567402-51-0 5-(4-chlorophenyl)-1-(2-methoxyphenyl)-3-{[1-(phenylcarbonyl)azetidin-3-yl]oxy}-1H-pyrazole 
• 1567402-54-3 4-[(3-{[5-(4-chlorophenyl)-1-(2-methoxyphenyl)-1H-pyrazol-3-yl]oxy}azetidin-1-yl)sulfonyl]-3,5-dimethylisoxazole 
• 1567402-85-0 3-(azetidin-3-yloxy)-5-(4-chlorophenyl)-1-(2-methoxyphenyl)-1H-pyrazole hydrochloride 

Relevant academic research and scientific papers

SUBSTITUTED PYRAZOLES AS N-TYPE CALCIUM CHANNEL BLOCKERS

Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein R1, R2, ring A, and G are defined herein.

REACTION OF 2-ARYLAZO-2,5-DIMETHYL-3(2H)-FURANONES WITH AMMONIA. PREPARATION OF β-ACETYL-β-(3-AMINO-2-BUTENOYL)ARYLHYDRAZINES.

Ring opening of 2-arylazo-2,5-dimethyl-3(2H)-furanones (1a-d) with ammonia leads to previously unknown β-acetyl-β-(3-amino-2-butenoyl)arylhydrazines (3a-d).The reaction mechanism is discussed.