79985-68-5Relevant academic research and scientific papers
Stereoselective synthesis of 9-trans-9-desmethyl-9-fluororetinals based on the four-components coupling approach
Shinada, Tetsuro,Sekiya, Noriko,Bojkova, Nina,Yoshihara, Kazuo
, p. 3675 - 3686 (1999)
9-trans-9-Desmethyl-9-fluororetinal analogs were synthesized by the four-components coupling approach. Homer-Emmons olefination of 3 afforded the undesired 2E-isomer 5 which was transformed to 6E-triene 8 via the Stille coupling reaction. Isomerization of
