79996-92-2

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
(3-BROMO-1-NAPHTHYL)METHANOL is used as a reagent in organic synthesis for the preparation of various pharmaceuticals and agrochemicals. Its unique structure allows for the creation of a wide range of compounds with different therapeutic and pesticidal properties.
Used in Fragrance and Dye Industries:
(3-BROMO-1-NAPHTHYL)METHANOL is also utilized in the production of fragrances and dyes due to its chemical composition, which can contribute to the development of novel scents and colorants.
Used in Medicinal and Biological Research:
(3-BROMO-1-NAPHTHYL)METHANOL has been studied for its potential anti-inflammatory and anti-cancer properties, making it an interesting compound for further research in the fields of medicine and biology. Its exploration in these areas could lead to the development of new treatments and therapies for various health conditions.

Upstream product

• 16726-66-2 3-bromo-1-naphthoic acid 
• 7757-82-6 sodium sulfate 
• 54978-07-3 3-nitro-1-naphthalenecarboxylic acid chloride 
• 88790-90-3 methyl 3-amino-5,6,7,8-tetrahydro-1-naphthoate 
• 13772-63-9 methyl 3-nitro-5,6,7,8-tetrahydro-1-naphthoate 
• 4507-84-0 3-nitro-1-naphthoic acid 
• 81-84-5 1,8-Naphthalic anhydride 
• 24050-49-5 3-bromonaphthalic-1,8-anhydride 
• 16650-63-8 3-bromo-naphthalene-1-carboxylic acid methyl ester 

Downstream Products

• 954410-14-1 C₃₈H₃₈FN₅O₅ 
• 954410-12-9 methyl 3-((3S)-3-(azidomethyl)-4-{[1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylphenyl)-1H-imidazol-4-yl]carbonyl}piperazin-1-yl)-1-naphthoate 
• 954410-06-1 [(2S)-1-{[1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylphenyl)-1H-imidazol-4-yl]carbonyl}-4-(4-{[(triisopropylsilyl)oxy]methyl}-2-naphthyl)piperazin-2-yl]methyl acetate 
• 79997-04-9 1-(bromomethyl)-3-cyanonaphthalene 

Relevant academic research and scientific papers

(PIPERIDIN-3-YL)(NAPHTHALEN-2-YL)METHANONE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF THE HISTONE DEMETHYLASE KDM2B FOR THE TREATMENT OF CANCER

The present invention relates to (piperidin-3-yl)(naphthalen-2-yl) methanone derivatives and related compounds as inhibitors of one or more histone demethylses, such as KDM2b. The invention also provides pharmaceutically acceptable compositions comprising

RENIN INHIBITORS

Renin inhibitors, which are spirocyclic piperidine amides, of structural formula (I) and pharmaceutical compositions thereof useful in the treatment of cardiovascular diseases and renal insufficiency, wherein n, for each instance in which it occurs, is independently 0, 1, or 2; R1 is hydrogen, C1-6 -alkyl or C3-6 -cycloalkyl, wherein said C1-6 -alkyl or C3-6 -cycloalkyl group can be independently substituted with 1-3 halogens; A is (i) a five- or six-membered saturated or unsaturated heterocyclic or carbocyclic monocyclic ring or (ii) a five- or six-membered saturated or unsaturated heterocyclic or carbocyclic ring which is fused to another five- or six-membered saturated or unsaturated heterocyclic or carbocyclic ring, V is a bond or -(C=O)-, -CH(OH)-, -CH2- or =CH-; U is a bond or -CH2-, or for the case when V is =CH-, U is -CH=; X is =CH-, =CF-, =C(OR3)-, or -C=O-; and Y is =CH-, =CF-, =N-, or for the case when X is -C=O-, Y is -N(R3)-.

NOVEL C-ARYL GLUCOSIDE SGLT2 INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

A novel C-aryl glucoside compound, or a pharmaceutically acceptable salt or a prodrug thereof having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney; and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly, diabetes, are provided.

Substituted Imidazole 4-Carboxamides as Cholecystokinin-1 Receptor Modulators

Certain novel substituted imidazole 4-carboxamides are ligands of the human cholecystokinin receptor and, in particular, are selective ligands of the human cholecystokinin-1 receptor (CCK-1R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of CCK-1R, such as obesity, and diabetes.

Synthesis, biological evaluation and molecular modelling studies of novel ACD- and ABD-ring steroidomimetics as inhibitors of CYP17

Two novel classes of non-steroidal substrate mimetics were synthesised and examined for their potency as inhibitors of human CYP17. Selected compounds were tested for inhibition of hepatic CYP enzymes 3A4, 1A2, 2C9 and 2C19. The most promising compound 15

SUBSTITUTED IMIDAZOLE 4-CARBOXAMIDES AS CHOLECYSTOKININ-1 RECEPTOR MODULATORS

Certain novel substituted imidazole 4-carboxamides are ligands of the human cholecystokinin receptor and, in particular, are selective ligands of the human cholecystokinin-1 receptor (CCK-1R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of CCK-1R, such as obesity, and diabetes.

2-naphthyl-carbapenem antibacterial agents

Carbapenems of the formula STR1 are useful antibacterial agents.

2-naphthyl-carbapenem antibacterial agents

Carbapenems of the formula STR1 are useful antibacterial agents.

Preparation of a series of substituted fluoromethylnaphthalenes

A series of 22 3- and 4-substituted 1-fluoromethylnaphthalenes have been synthesized.Details of practical procedures for the preparation of all intermediates are described, and physical properties for all of the substituted naphthalenes synthesized, and spectral parameters for 51 previously unknown compounds, are given.