80-60-4

Usage

Uses

Used in Pharmaceutical Research and Development:
DL-2-aminobutyric acid is used as a research compound for studying the effects of GABA on neurological function, aiding in the development of potential treatments for conditions such as anxiety, epilepsy, and neuropathic pain.
Used in Neurotransmitter Modulation Studies:
It is employed as a tool in research to understand its potential role in modulating neurotransmitter activity in the brain, which could lead to advancements in the treatment of neurological disorders.
Used in Metabolic Disorder Research:
DL-2-aminobutyric acid is used as a potential biomarker in the study of certain metabolic disorders, helping to identify and monitor these conditions more effectively.
Used in Pharmaceutical Production:
DL-2-AMINOBUTYRIC ACID may be utilized in the manufacturing process of pharmaceuticals, particularly those targeting the central nervous system and related disorders.

InChI:InChI=1S/C4H9NO2/c1-2-3(5)4(6)7/h3H,2,5H2,1H3,(H,6,7)

Upstream product

• 2835-81-6 2-aminobutanoic acid 
• 89603-48-5 2-amino butyramide hydrochloride 
• 7682-14-6 N-acetyl-D-2-aminobutyric acid 

Relevant academic research and scientific papers

METHOD OF SEPARATING AND COLLECTING OPTICALLY ACTIVE AMINO ACID AMIDE

[PROBLEMS] To provide a method of efficiently separating and collecting an optically active amino acid amide and an optically active amino acid, which are highly important substances as intermediates in producing various industrial products, pesticides and medicines, from an aqueous solution containing the optically active amino acid amide and the optically active amino acid. [MEANS FOR SOLVING PROBLEMS] In separating and collecting an optically active amino acid amide from an aqueous solution containing the optically active amino acid amide and an optically active amino acid by using the difference in solubility in an organic solvent between the optically active amino acid amide and the optically active amino acid, the separation/collection procedures are carried out, without desalting the aqueous solution or after desalting the same, under such conditions that the ratio (C/A) of the sum of the anionic equivalents (A) contained in the aqueous solution to the sum of the cation equivalents (C) ranges from 0.95 to 1.05 in the case of the non-desalted aqueous solution, or from 0.5 to 1.5 in the case of the desalted aqueous solution.

Racemic Structures of Organic Ammonium Salts of N-Acetyl-DL-2-aminobutyric Acid and N-Acetyl-DL-norvaline and Optical Resolution by Preferential Crystallization of DL-Ammonium Salts

The racemic structures of the ammonium salts (AM salts) and seven organic ammonium salts of N-acetyl-DL-2-aminobutyric acid (Dl-AcAbu) and N-acetyl-DL-norvaline (DL-AcNva) were studied on the basis of thermodynamic analyses to explore the possibility of optical resolution by preferential crystallization.An empirical equation has been derived from thermodynamic data and melting points of ammonium and organic ammonium salts of N-acyl-DL-amino acids to predict racemic structure around room temperature.The AM salts of DL-AcAbu and -AcNva exist in conglomerate around room temperature.It is possible to resolve optically these DL-AM salts by preferential crystallization in ethanol at 10 deg C, and the succesive preferential crystallization followed by purification gave D- and L-2-aminobutyric acids and -norvalines with optical purities close to 100percent.