80008-52-2

Upstream product

• 43153-76-0 1-(2-mercaptophenyl)-pyrrole 
• 107-14-2 chloroacetonitrile 
• 43153-75-9 bis(2-N-pyrrolylphenyl) disulfide 
• 696-59-3 cis,trans-2,5-dimethoxytetrahydrofuran 
• 137-07-5 2-amino-benzenethiol 
• 43153-83-9 N-(2-methylthiophenyl)pyrrole 
• 2987-53-3 2-(Methylthio)aniline 

Downstream Products

• 107344-57-0 (2-Pyrrol-1-yl-benzenesulfinyl)-acetonitrile 
• 80008-51-1 1-(2-carbossimetiltiofenil)pirrolo 
• 80008-58-8 1-(2-cianometiltiofenil)pirrolo-2-carbaldeide 
• 80008-55-5 4,5-diidro-4-idrossipirrolo<2,1-d><1,5>benzotiazepina 
• 80008-53-3 pirrolo<2,1-d><1,5>benzotiazepin-4(5H)-one 
• 80008-60-2 pirrolo<2,1-d><1,5>benzotiazepin-5-carbossamide 

Relevant academic research and scientific papers

Synthesis of 4H-Pyrrolobenzothiazines and 3-(Methylthio)oxindoles

The Pummerer reaction was carried out with α-acylsulfides and phenyl iodosyl bis(trifluoroacetate) instead of α-acylsulfoxides to prepare 4H-pyrrolobenzothiazines and 3-(methylthio)oxindoles.

Intramolecular Capture of Pummerer Rearrangement Intermediates. I. Synthesis of Pyrrolobenzothiazines

Treatment of 1-(2-alkylsulfinylphenyl)pyrroles with trifluoroacetic acid in refluxing toluene gives 4-substituted pyrrolobenzothiazines in good yield when the alkyl group bears an electron withdrawing substituent on the α-carbon.In the absence