8003-05-2

Basic information

• Product Name: PHENYLMERCURIC NITRATE
• Synonyms: Mercuriphenyl nitrate;PHENYLMERCURIC NITRATE;PHENYLMERCURIC NITRATE, BASIC;PHENYLMERCURY NITRATE;PHENYLMERCURY NITRATE BASIC;cmpd.withhydroxyphenylmercury(1:1);dz;Gyne-merfen
• CAS NO: 8003-05-2
• Molecular Formula: C12H11Hg2NO4
• Molecular Weight: 634.4
• EINECS: 200-242-9
• Mol File: 8003-05-2.mol
• Article Data: 0

Chemical Properties

• Melting Point: 175-185 °C (dec.)(lit.)
• Appearance: /
• Vapor Pressure: 0.0000019 hPa at 20°C
• Storage Temp.: Store below +30°C.
• Water Solubility: slightly
• Merck: 14,7302
• CAS DataBase Reference: PHENYLMERCURIC NITRATE(CAS DataBase Reference)
• NIST Chemistry Reference: PHENYLMERCURIC NITRATE(8003-05-2)
• EPA Substance Registry System: PHENYLMERCURIC NITRATE(8003-05-2)

Safety Data

• Hazard Codes: T,N
• Statements: 25-34-48/24/25-50/53
• Safety Statements: 23-24/25-37-45-60-61
• RIDADR: UN 1895 6.1/PG 2
• WGK Germany: 3
• RTECS: OW8575000
• HazardClass: 6.1
• PackingGroup: II
• Hazardous Substances Data: 8003-05-2(Hazardous Substances Data)

Usage

Chemical Properties

white powder

Uses

Pharmaceutic aid (antimicrobial). Tree wound dressing.

General Description

Phenylmercury nitrate is a mercury-based organic compound known to have antibacterial and antifungal activities. It is also used as a preservative for parenteral injections.

Clinical Use

Phenylmercuric nitrate is a mixture of phenylmercuric nitrateand phenylmercuric hydroxide. It occurs as a whitecrystalline material that is sparingly soluble in water andslightly soluble in alcohol. It is used in concentrations of1:10,000 to 1:50,000 to preserve injectable drugs againstbacterial contamination. A disadvantage to organomercurialsis that their bacteriostatic efficacy is reduced in the presenceof serum.

Purification Methods

When recrystallised from water or aqueous EtOH, it has m 191-191.5o, and from 95% EtOH it has m 186.5o [Challanger & Rothstein J Chem Soc I 1258 1934]. When recrystallised from *C6H6 or CHCl3, it has m 131-131.5o [Morton et al. J Am Chem Soc 69 908 1947.] [Beilstein 16 III 1348, 16 IV 1721.]

InChI:InChI=1/2C6H5.2Hg.NO3.H2O/c2*1-2-4-6-5-3-1;;;2-1(3)4;/h2*1-5H;;;;1H2/q;;;;-1;/r2C6H5Hg.NO3.H2O/c2*7-6-4-2-1-3-5-6;2-1(3)4;/h2*1-5H;;1H2/q;;-1;

Related news

Determination of PHENYLMERCURIC NITRATE (cas 8003-05-2) by Potentiometric Titration07/12/2019

A procedure was developed for measuring small amounts of phenylmercuric nitrate in aqueous solutions. The method depends on the formation of insoluble phenylmercuric iodide upon titration of phenylmercuric nitrate with potassium iodide. The end-point can be detected using an iodide-sensitive ele...detailed

Antifungal effect of ophthalmic preservatives PHENYLMERCURIC NITRATE (cas 8003-05-2) and benzalkonium chloride on ocular pathogenic filamentous fungi07/11/2019

In the present study, the antifungal effects of phenylmercuric nitrate and benzalkonium chloride versus those of natamycin and ketoconazole were assessed against 216 filamentous fungi isolates from cases of fungal keratitis. They included 112 Fusarium isolates, 94 Aspergillus isolates, and 10 Al...detailed