80038-65-9

Basic information

• Product Name: 1-[4-(octahydroquinolin-1(2H)-yl)butyl]-1,5-dihydroquinoline
• CAS NO: 80038-65-9
• Molecular Formula: C₂₂H₃₂N₂
• Molecular Weight: 324.5029
• Mol File: 80038-65-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 510.8°C at 760 mmHg
• Flash Point: 232.9°C
• Density: 1.07g/cm³
• Vapor Pressure: 1.51E-10mmHg at 25°C
• Refractive Index: 1.595
• CAS DataBase Reference: 1-[4-(octahydroquinolin-1(2H)-yl)butyl]-1,5-dihydroquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(octahydroquinolin-1(2H)-yl)butyl]-1,5-dihydroquinoline(80038-65-9)
• EPA Substance Registry System: 1-[4-(octahydroquinolin-1(2H)-yl)butyl]-1,5-dihydroquinoline(80038-65-9)

Safety Data

• Hazardous Substances Data: 80038-65-9(Hazardous Substances Data)

Usage

Chemical class

Quinoline derivatives

Structure

Complex organic molecule with a heterocyclic structure

Components

Contains both quinoline and octahydroquinoline moieties

Potential applications

Pharmaceutical and medicinal chemistry

Biological activities

May have anti-inflammatory, analgesic, or antimicrobial properties

Further research

Studies are needed to explore potential uses and effects of the compound
Please note that this list is based on the provided material and may not be exhaustive. Further research and studies are required to fully understand the properties and potential applications of this chemical compound.

Upstream product

• 110-52-1 1,4-dibromo-butane 
• 91-22-5 quinoline 

Relevant articles and documents

Preparation, in vitro screening and molecular modelling of symmetrical bis-quinolinium cholinesterase inhibitors - Implications for early Myasthenia gravis treatment

This paper describes the preparation and in vitro evaluation of 18 newly prepared bis-quinolinium inhibitors on human recombinant acetylcholinesterase (AChE) and human plasmatic butyrylcholinesterase (BChE). Their inhibitory (IC50) and was compared to the chosen standards ambenonium dichloride, edrophonium chloride, BW284c51 and ethopropazine hydrochloride. One novel compound was found to be a promising inhibitor of hAChE (in nM range) and was better than edrophonium chloride or BW284c51, but was worse than ambenonium chloride. This compound also showed selectivity towards hAChE and it was confirmed as a non-competitive inhibitor of hAChE by kinetic analysis. A molecular modelling study further confirmed its binding to the peripheral active site of hAChE via apparent π-π or π-cationic interactions.