800401-84-7

Basic information

• Product Name: 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-chloro-
• Synonyms: 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-chloro-;5-Chloro-7-Azaindole-2-carboxylic acid;3-b]pyridine-2-carboxylicacid;5-chloro-1H-pyrrolo[2;5-chloro-1H-pyrrolo[2,3-b]pyridine-2-carbo×ylic acid;5-chloro-3H-pyrrolo[2,3-b]pyridine-2-carboxylic acid
• CAS NO: 800401-84-7
• Molecular Formula: C₈H₅ClN₂O₂
• Molecular Weight: 196.59
• Mol File: 800401-84-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.644 g/cm³
• Refractive Index: 1.744
• Storage Temp.: 2-8°C
• PKA: 3.84±0.30(Predicted)
• CAS DataBase Reference: 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-chloro-(800401-84-7)
• EPA Substance Registry System: 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-chloro-(800401-84-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 800401-84-7(Hazardous Substances Data)

Usage

Uses

5-Chloro-1h-pyrrolo[2,3-b]pyridine-2-carboxylic acid

InChI:InChI=1/C8H5ClN2O2/c9-5-1-4-2-6(8(12)13)11-7(4)10-3-5/h1-3H,(H,10,11)(H,12,13)

Upstream product

• 127-17-3 2-oxo-propionic acid 
• 211308-81-5 5-chloro-3-iodo-2-aminopyridine 
• 1072-98-6 5-chloro-2-pyridylamine 

Downstream Products

• 800401-18-7 2-(S)-[(5-chloro-1H-pyrrolo[2,3-b]pyridine-2-carbonyl)amino]-3-(4-fluorophenyl)propionic acid 
• 1083181-28-5 C₁₀H₉ClN₂O₂ 
• 1399297-47-2 ethyl 5-chloro-1-methyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylate 

Relevant articles and documents

BICYCLIC HETEROAROMATIC AMIDE COMPOUNDS AND USES THEREOF

The present invention features compounds useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.

PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSHORYLASE

Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are inhibitors of glycogen phosphorylase and are useful in the prophylactic or therapeutic treatment of diabetes, hyperglycemia, hypercholesterolemia, hyperinsulinemia, hyperlipidemia, hypertension, atherosclerosis or tissue ischemia e.g. myocardial ischemia, and as cardioprotectants.