80054-66-6Relevant academic research and scientific papers
Expedient and efficient one pot synthesis of trifluoroethyl ethers from metal free 2,4,6-tris-(2,2,2-trifluoro-ethoxy)-[1,3,5] triazene
Mangawa, Shrawan Kumar,Sharma, Chiranjeev,Singh, Ashawani Kumar,Awasthi, Satish K.
, p. 35042 - 35045 (2015/05/04)
An efficient synthesis of fluorinated alkyl and aryl ethers was achieved by the use of s-triazene derived fluorinated reagent 2,4,6-tris-(2,2,2-trifluoro-ethoxy)-[1,3,5] triazene (TriTFET). The procedure offers a very attractive alternative for the synthesis of fluorinated motifs that are found in various bioactive molecules. Moreover, TriTFET is a synthetic non-toxic, non-ozone depleting and stable reagent. All compounds were characterized by 1H, 13C and 19F NMR.
Synthesis of trifluoroethyl ethers from 2,2,2-trifluoroethyl chloride (HCFC-133a) in high temperature aqueous medium
Wu, Kai,Chen, Qing-Yun
, p. 79 - 83 (2007/10/03)
Treatment of 2,2,2-trifluoroethyl chloride (HCFC-133a) with alcohols (phenols) and aqueous KOH in autoclave at 240-280 C gives the corresponding 2,2,2-trifluoroethyl (2-chloro-1,1-difluoroethyl) ethers in good yields.
