80063-85-0Relevant academic research and scientific papers
meso (Methine) Functionalization of Octa-alkylporphyrins
Smith, Kevin M.,Bisset, Graham M. F.
, p. 2625 - 2630 (1981)
meso-Acetoxymethylocta-alkylporphyrins react with a variety of nucleophiles such as alcohols (to give the corresponding alkoxymethylporphyrins), amines (yielding aminomethylporphyrins), and Grignard reagents (to give meso-alkylporphyrins).Treatment of the meso-acetoxymethylporphyrins with thiol reagents accomplishes reduction to give the meso-methylporphyrin rather than the sulphide.Making use of these meso-functionalization reactions, potential cytochrome P450 models and a model for the tense form of hemoglobin are synthesized.
