meso (Methine) Functionalization of Octa-alkylporphyrins

DOI: 10.1039/P19810002625

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 2625 - 2630 (1981)

Update date:2022-08-03

Topics:

Authors:

Smith, Kevin M.

Bisset, Graham M. F.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/P19810002625

meso-Acetoxymethylocta-alkylporphyrins react with a variety of nucleophiles such as alcohols (to give the corresponding alkoxymethylporphyrins), amines (yielding aminomethylporphyrins), and Grignard reagents (to give meso-alkylporphyrins).Treatment of the meso-acetoxymethylporphyrins with thiol reagents accomplishes reduction to give the meso-methylporphyrin rather than the sulphide.Making use of these meso-functionalization reactions, potential cytochrome P450 models and a model for the tense form of hemoglobin are synthesized.

Full text of DOI:10.1039/P19810002625

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:meso-(benzyloxymethyl)octaethylporphyrin

Cas No:80063-85-0

R&D Labs maybe for 80063-85-0

HANGZHOU ICH BIOFARM CO.,LTD

Contact:+86-571-28186845

Address:Room 1224,Eastcom Mansion,398 Wensan Road,Hangzhou,310013 China
lianyungang jinkang pharmaceutical technology co., ltd.

Contact:008651885445517

Address:Jinshan industrial park, Ganyu county, Lianyungang, Jiangsu Province, 222115, China
Quzhou Aokai Chemical Co., Ltd.

Contact:86-570-3032832

Address:NO.16 , Laodong Road,Quzhou City, Zhejiang Province,China
TIANJIN DONGRUXIANG MINERALS MARKETING CO.,LTD(expird)

Contact:22-58516360

Address:tianjin
New Forms

Contact:+31-24-3886056

Address:Binderskampweg 29 Unit 36

Relevant to this article

Reaction of a Silyl-Copper Reagent with Acetylenes: a New Synthesis of Vinylsilanes

Doi:10.1039/c39800000276
(1980)
CHEMISTRY OF NITRO IMIDES. 1. GENERAL METHOD FOR THE SYNTHESIS OF NITRO IMIDES

Doi:10.1007/BF00949479
(1981)
HIGHLY STEREOSELECTIVE CONSTRUCTION OF CHIRAL QUATERNARY CARBON: ASYMMETRIC SYNTHESIS OF β,β-DISUBSTITUTED γ-BUTYROLACTONES

Doi:10.1246/cl.1981.1621
(1981)
PREPARATION AND DIELS-ALDER REACTIVITY OF ETHYL-β-PHENYLSULFONYLPROPIOLATE

Doi:10.1016/S0040-4039(01)81901-8
(1981)
ADDITION OF ELEMENTAL SELENIUM TO PHOSPHONATE CARBANIONS- A KEY STEP IN THE SYNTHESIS OF VINYLPHOSPHONATES. A NEW SYNTHETIC APPROACH TO 1,4-DICARBONYL SYSTEMS.

Doi:10.1016/S0040-4039(01)81837-2
(1981)
Drugs derived from Cannabinoids. Part 8. The Synthesis of Side-chain Analogues of Δ^6a,10a-Tetrahydrocannabinol

Doi:10.1039/P19810002825
(1981)

Article Doi