80076-46-6 Usage
Description
5,6-Difluoro-1,2,3,4-tetrahydro-2-methylquinoline is a chemical compound belonging to the quinoline family, characterized by the molecular formula C11H11F2N. It features a quinoline ring with two fluorine atoms and a methyl group attached, endowing it with unique chemical properties. 5,6-Difluoro-1,2,3,4-tetrahydro-2-methylquinoline is recognized for its potential in pharmaceutical and agrochemical applications, primarily serving as a building block in the synthesis of various organic molecules and pharmaceuticals.
Uses
Used in Pharmaceutical Industry:
5,6-Difluoro-1,2,3,4-tetrahydro-2-methylquinoline is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs. Its unique structure allows for specific interactions with biological targets, potentially leading to the creation of novel therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 5,6-Difluoro-1,2,3,4-tetrahydro-2-methylquinoline is utilized as a precursor in the production of agrochemicals, such as pesticides and herbicides. Its incorporation can enhance the effectiveness of these products by improving their chemical stability and biological activity against target organisms.
Used in Drug Discovery:
5,6-Difluoro-1,2,3,4-tetrahydro-2-methylquinoline plays a significant role in drug discovery as a structural component of potential lead compounds. Its presence in molecular scaffolds can influence the pharmacokinetics and pharmacodynamics of drug candidates, facilitating the identification of new therapeutic agents.
Used in Material Science:
5,6-Difluoro-1,2,3,4-tetrahydro-2-methylquinoline is also used in the development of new materials and chemical processes within material science. Its unique structure and properties can contribute to the creation of advanced materials with specific characteristics, such as improved stability or reactivity.
Overall, 5,6-Difluoro-1,2,3,4-tetrahydro-2-methylquinoline is a versatile chemical entity with broad applications across various industries, particularly in the development of pharmaceuticals and agrochemicals, as well as in material science and chemical research.
Check Digit Verification of cas no
The CAS Registry Mumber 80076-46-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,0,7 and 6 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 80076-46:
(7*8)+(6*0)+(5*0)+(4*7)+(3*6)+(2*4)+(1*6)=116
116 % 10 = 6
So 80076-46-6 is a valid CAS Registry Number.
InChI:InChI=1S/C10H11F2N/c1-6-2-3-7-9(13-6)5-4-8(11)10(7)12/h4-6,13H,2-3H2,1H3
80076-46-6Relevant articles and documents
Synthesis, antibacterial activities, mode of action and acute toxicity studies of new oxazolidinone-fluoroquinolone hybrids
Liu, Lili,Shao, Liping,Li, Jing,Cui, Haifeng,Li, Bing,Zhou, Xuzheng,Lv, Pengyue,Zhang, Jiyu
, (2019/05/01)
To combat bacterial resistance, a series of new oxazolidinone-fluoroquinolone hybrids have been synthesized and characterized. All synthetic hybrids were preliminarily evaluated for their in vitro antibacterial activities against 6 standard strains and 3 clinical isolates. The majority of hybrids displayed excellent activities against Gram-positive bacteria, but limited activities against Gram-negative bacteria. Hybrids OBP-4 and OBP-5 were found to be the most promising compounds. Further, in vitro antibacterial activities, mode of action and acute toxicity in mice of hybrids OBP-4 and OBP-5 were investigated. Hybrids OBP-4 and OBP-5 exhibited potent activities against Gram-positive bacteria, including drug-resistant strains. Correspondingly, studies on the mode of action of hybrids OBP-4 and OBP-5 indicated a strong inhibitory activity on protein synthesis by binding the active site of 50S subunit, but a weak inhibitory action on DNA synthesis. In addition, LD50 values of hybrids OBP-4 and OBP-5 in the acute oral toxicity were larger than 2000 mg/kg, suggesting a good safety profile.
