80089-24-3Relevant academic research and scientific papers
Efficient asymmetric organocatalytic formation of erythrose and threose under aqueous conditions
Burroughs, Laurence,Vale, Matthew E.,Gilks, James A. R.,Forintos, Henrietta,Hayes, Christopher J.,Clarke, Paul A.
supporting information; experimental part, p. 4776 - 4778 (2010/09/05)
Esters of proteinogenic amino acids efficiently catalyse the formation of erythrose and threose under aqueous conditions in the highest yields and enantioselectivities yet reported. Remarkably while esters of (l)-proline yield (l)-carbohydrates, esters of (l)-leucine and (l)-alanine generate (d)-carbohydrates, offering the potential to account for the prebiotic link between natural (l)-amino acids and natural (d)-sugars.
Heterocyclic Compounds as MEK Inhibitors
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Page/Page column 53-54, (2009/12/02)
The present invention relates to compounds of formula I and pharmaceutically acceptable salts. These compounds can act as potential MEK inhibitors in the treatment of hyperproliferative diseases, like cancer and inflammation. The present invention also reveals methods of preparation thereof.
The discovery of an enantioselective receptor for (-)-adenosine from a racemic dynamic combinatorial library
Voshell, Sharon M.,Lee, Stephen J.,Gagne, Michel R.
, p. 12422 - 12423 (2007/10/03)
The use of laser polarimetry detection coupled with HPLC is demonstrated to enable the discovery of enantioselective receptors from racemic dynamic combinatorial libraries. Templating with an enantiopure analyte, such as (-)-adenosine, leads to amplificat
