80089-36-7

Basic information

• Product Name: 1-propionyl-2-(2-phenoxyethyl)pyrrolidine
• Synonyms: 1-propionyl-2-(2-phenoxyethyl)pyrrolidine
• CAS NO: 80089-36-7
• Molecular Weight: 247.337
• Mol File: 80089-36-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-propionyl-2-(2-phenoxyethyl)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-propionyl-2-(2-phenoxyethyl)pyrrolidine(80089-36-7)
• EPA Substance Registry System: 1-propionyl-2-(2-phenoxyethyl)pyrrolidine(80089-36-7)

Safety Data

• Hazardous Substances Data: 80089-36-7(Hazardous Substances Data)

Upstream product

• 19432-88-3 2-(β-hydroxyethyl)-pyrrolidine 
• 802294-64-0 propionic acid 
• 108-95-2 phenol 

Downstream Products

• 19432-88-3 2-(β-hydroxyethyl)-pyrrolidine 

Relevant articles and documents

Participation of a Neighboring Amide Group in the Hydrolytic C-OAr Cleavage of 1-Acyl-2-(2-phenoxyethyl)pyrrolidines

Measurements are reported on the kinetics of acid-catalyzed hydrolysis of 1-acetyl- and 1-propionyl-2-(2-phenoxyethyl)pyrrolidine.The pseudo-first-order rate constants, kobs, were obtained: kobs = kA + kB, where kA and kB refer to the rate constants for the formation of 2-(2-phenoxyethyl)pyrrolidine A and 2-(2-hydroxyethyl)pyrrolidine B, respectively.Formation of the product B with consequent liberation of the phenol is attributed to the effect of neighboring amide group participation.A mechanism comprising a six-membered cyclic intermediate has been proposed for hydrolysis leading to cleavage of the ether bond.